Overview

  • Product nameAnti-CD14 antibody [B-A8]
    See all CD14 primary antibodies
  • Description
    Mouse monoclonal [B-A8] to CD14
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Monocytes (Human)

Properties

Applications

Our Abpromise guarantee covers the use of ab27388 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notesFlow Cyt: Use 10µl for 106 cells or 100 µl of whole blood.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionCooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
    • Tissue specificityExpressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
    • Sequence similaritiesContains 11 LRR (leucine-rich) repeats.
    • Post-translational
      modifications
      N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD 14 antibody
      • CD_antigen=CD14 antibody
      • CD14 antibody
      • CD14 antigen antibody
      • CD14 molecule antibody
      • CD14_HUMAN antibody
      • LPS-R antibody
      • Mo2 antibody
      • Monocyte differentiation antigen CD14 antibody
      • Monocyte differentiation antigen CD14 urinary form antibody
      • Monocyte differentiation antigen CD14, membrane-bound form antibody
      • Myeloid cell specific leucine rich glycoprotein antibody
      • Myeloid cell-specific leucine-rich glycoprotein antibody
      see all

    Anti-CD14 antibody [B-A8] images

    • A typical staining pattern of monocytes using ab27388.

    References for Anti-CD14 antibody [B-A8] (ab27388)

    This product has been referenced in:
    • Game DS  et al. CD4+CD25+ regulatory T cells do not significantly contribute to direct pathway hyporesponsiveness in stable renal transplant patients. J Am Soc Nephrol 14:1652-61 (2003). Read more (PubMed: 12761268) »

    See 1 Publication for this product

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    For the anti-CD14, as described in literature and in all documentation, the CD14 is highly expressed on monocyte/macrophage and also, but around 10 times less, on neutrophils (that is to say quite all the sub-popul...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"