Anti-CD14 antibody [MEM-18] (Phycoerythrin) (ab18274)

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Overview

  • Product name
    Anti-CD14 antibody [MEM-18] (Phycoerythrin)
    See all CD14 primary antibodies
  • Description
    Mouse monoclonal [MEM-18] to CD14 (Phycoerythrin)
  • Host species
    Mouse
  • Conjugation
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human, Monkey
    Predicted to work with: Non human primates
  • Immunogen

    A crude mixture of urinary proteins precipitated from the urine of a patient suffering from proteinuria (Human).

Applications

Our Abpromise guarantee covers the use of ab18274 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notes
    Flow Cyt: Use at a concentration of 200 µl/ml whole blood.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • Function
      Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
    • Tissue specificity
      Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
    • Sequence similarities
      Contains 11 LRR (leucine-rich) repeats.
    • Post-translational
      modifications
      N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
      • Alternative names
        • CD 14 antibody
        • CD_antigen=CD14 antibody
        • CD14 antibody
        • CD14 antigen antibody
        • CD14 molecule antibody
        • CD14_HUMAN antibody
        • LPS-R antibody
        • Mo2 antibody
        • Monocyte differentiation antigen CD14 antibody
        • Monocyte differentiation antigen CD14 urinary form antibody
        • Monocyte differentiation antigen CD14, membrane-bound form antibody
        • Myeloid cell specific leucine rich glycoprotein antibody
        • Myeloid cell-specific leucine-rich glycoprotein antibody
        see all

      References

      ab18274 has not yet been referenced specifically in any publications.

      Publishing research using ab18274? Please let us know so that we can cite the reference in this datasheet.

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