Anti-CD14 antibody [MEM-18] (Phycoerythrin) (ab18274)

Overview

• Product name
  Anti-CD14 antibody [MEM-18] (Phycoerythrin)
  See all CD14 primary antibodies
• Description
  Mouse monoclonal [MEM-18] to CD14 (Phycoerythrin)
• Conjugation
  Phycoerythrin. Ex: 488nm, Em: 575nm
• Tested applications
  Suitable for: Flow Cytmore details
• Species reactivity
  Reacts with: Human, Monkey
  Predicted to work with: Non human primates
• Immunogen

  A crude mixture of urinary proteins precipitated from the urine of a patient suffering from proteinuria (Human).

Properties

• Form
  Liquid
• Storage instructions
  Shipped at 4°C. Store at +4°C.
• Storage buffer
  Preservative: 15mM Sodium Azide
  Constituents: PBS, BSA. pH 7.4
• Concentration information loading...
• Clonality
  Monoclonal
• Clone number
  MEM-18
• Isotype
  IgG1
• Research areas
  • Immunology
  • Cell Type Markers
  • CD
  • Myeloid Cells

  • Stem Cells
  • Hematopoietic Progenitors
  • Hematopoietic Stem Cells
  • Human Lineage Negative

  • Stem Cells
  • Mesenchymal Stem Cells
  • Negative Markers

  • Stem Cells
  • Hematopoietic Progenitors
  • Myeloid
  • Monocytic Lineage

  • Stem Cells
  • Hematopoietic Progenitors
  • Myeloid
  • Neutrophil Lineage

  • Immunology
  • Innate Immunity
  • TLR Signaling

  • Stem Cells
  • Endothelial Progenitors
  • Endothelial Markers

  • Kits/ Lysates/ Other
  • Kits
  • ELISA Kits
  • ELISA Kits
  • CD markers ELISA kits

Associated products

• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

Applications

Target

• Function
  Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
• Tissue specificity
  Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
• Sequence similarities
  Contains 11 LRR (leucine-rich) repeats.
• Post-translational
  modifications
  N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
• Cellular localization
  Cell membrane.

• Target information above from: UniProt accession P08571 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• Database links
  • Entrez Gene: 929 Human
  • Omim: 158120 Human
  • SwissProt: P08571 Human
  • Unigene: 163867 Human
• Alternative names
  • CD 14 antibody
  • CD_antigen=CD14 antibody
  • CD14 antibody

  • CD14 antigen antibody
  • CD14 molecule antibody
  • CD14_HUMAN antibody
  • LPS-R antibody
  • Mo2 antibody
  • Monocyte differentiation antigen CD14 antibody
  • Monocyte differentiation antigen CD14 urinary form antibody
  • Monocyte differentiation antigen CD14, membrane-bound form antibody
  • Myeloid cell specific leucine rich glycoprotein antibody
  • Myeloid cell-specific leucine-rich glycoprotein antibody

  see all

Protocols

• Flow cytometry protocols