Validated using a knockout cell line

Anti-CD146 antibody [EPR3208] (ab75769)

Publishing research using ab75769? Please let us know so that we can cite the reference in this datasheet.

ab75769 has been referenced in 42 publications.

  • Chen X  et al. Mechanical stretch-induced osteogenic differentiation of human jaw bone marrow mesenchymal stem cells (hJBMMSCs) via inhibition of the NF-?B pathway. Cell Death Dis 9:207 (2018). PubMed: 29434225
  • Zhang S  et al. Effects of platelet-rich plasma on the activity of human menstrual blood-derived stromal cells in vitro. Stem Cell Res Ther 9:48 (2018). ICC/IF . PubMed: 29482651
  • Huang X  et al. Rho/Rho-associated protein kinase signaling pathway-mediated downregulation of runt-related transcription factor 2 expression promotes the differentiation of dental pulp stem cells into odontoblasts. Exp Ther Med 15:4457-4464 (2018). PubMed: 29731830
  • Matsui M  et al. CD146 positive human dental pulp stem cells promote regeneration of dentin/pulp-like structures. Hum Cell 31:127-138 (2018). IHC . PubMed: 29313241
  • Liu Y  et al. Nrf2 Inhibits Periodontal Ligament Stem Cell Apoptosis under Excessive Oxidative Stress. Int J Mol Sci 18:N/A (2017). PubMed: 28513573
  • Xu L  et al. Different Angiogenic Potentials of Mesenchymal Stem Cells Derived from Umbilical Artery, Umbilical Vein, and Wharton's Jelly. Stem Cells Int 2017:3175748 (2017). PubMed: 28874910
  • Jacques C  et al. Targeting the epigenetic readers in Ewing sarcoma inhibits the oncogenic transcription factor EWS/Fli1. Oncotarget 7:24125-40 (2016). IHC . PubMed: 27006472
  • Amatori S  et al. Polyphenol-rich strawberry extract (PRSE) shows in vitro and in vivo biological activity against invasive breast cancer cells. Sci Rep 6:30917 (2016). WB . PubMed: 27498973
  • Berman R  et al. MUC18 Regulates Lung Rhinovirus Infection and Inflammation. PLoS One 11:e0163927 (2016). WB ; Mouse . PubMed: 27701461
  • Kang CM  et al. Genetic Comparison of Stemness of Human Umbilical Cord and Dental Pulp. Stem Cells Int 2016:3453890 (2016). PubMed: 27087814
  • Kawasaki T  et al. Six1 is required for mouse dental follicle cell and human periodontal ligament-derived cell proliferation. Dev Growth Differ N/A:N/A (2016). IF . PubMed: 27241908
  • Shen J  et al. Pericyte Antigens in Perivascular Soft Tissue Tumors. Int J Surg Pathol 23:638-48 (2015). IHC-P ; Human . PubMed: 26085647
  • Freeman FE  et al. Effects of in vitro endochondral priming and pre-vascularisation of human MSC cellular aggregates in vivo. Stem Cell Res Ther 6:218 (2015). IHC-P . PubMed: 26541817
  • Li YL  et al. Enhanced Protective Effect of the Combination of Uncaria and Semen Raphani on Vascular Endothelium in Spontaneously Hypertensive Rats. Evid Based Complement Alternat Med 2015:358352 (2015). PubMed: 26539222
  • Kostallari E  et al. Pericytes in the myovascular niche promote post-natal myofiber growth and satellite cell quiescence. Development 142:1242-53 (2015). IHC-Fr, ICC/IF . PubMed: 25742797
  • Ellison TS  et al. Suppression of ß3-integrin in mice triggers a neuropilin-1-dependent change in focal adhesion remodelling that can be targeted to block pathological angiogenesis. Dis Model Mech 8:1105-19 (2015). IHC-P ; Mouse . PubMed: 26159543
  • Haney MJ  et al. Exosomes as drug delivery vehicles for Parkinson's disease therapy. J Control Release 207:18-30 (2015). IHC ; Mouse . PubMed: 25836593
  • Hu L  et al. IGF1 Promotes Adipogenesis by a Lineage Bias of Endogenous Adipose Stem/Progenitor Cells. Stem Cells 33:2483-95 (2015). IF, IHC-P ; Human . PubMed: 26010009
  • DU H  et al. Cross-talk between endothelial and tumor cells via basic fibroblast growth factor and vascular endothelial growth factor signaling promotes lung cancer growth and angiogenesis. Oncol Lett 9:1089-1094 (2015). IF . PubMed: 25663861
  • Lee CH  et al. Harnessing endogenous stem/progenitor cells for tendon regeneration. J Clin Invest 125:2690-701 (2015). PubMed: 26053662
  • Huisman SA  et al. Fasting protects against the side effects of irinotecan but preserves its anti-tumor effect in Apc15lox mutant mice. Cell Cycle 14:2333-9 (2015). PubMed: 25955194
  • Sawitza I  et al. Bile acids induce hepatic differentiation of mesenchymal stem cells. Sci Rep 5:13320 (2015). ICC/IF . PubMed: 26304833
  • Chu HW  et al. CRISPR-Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18. Gene Ther 22:822-9 (2015). WB . PubMed: 26043872
  • Kawakami-Schulz SV  et al. Serum response factor: positive and negative regulation of an epithelial gene expression network in the destrin mutant cornea. Physiol Genomics 46:277-89 (2014). PubMed: 24550211
  • Ali SR  et al. Developmental heterogeneity of cardiac fibroblasts does not predict pathological proliferation and activation. Circ Res 115:625-35 (2014). IF, Flow Cyt ; Mouse . PubMed: 25037571
  • Kilcoyne KR  et al. Fetal programming of adult Leydig cell function by androgenic effects on stem/progenitor cells. Proc Natl Acad Sci U S A 111:E1924-32 (2014). IHC-P . PubMed: 24753613
  • Gamblin AL  et al. Bone tissue formation with human mesenchymal stem cells and biphasic calcium phosphate ceramics: The local implication of osteoclasts and macrophages. Biomaterials 35:9660-7 (2014). IHC-P ; Mouse . PubMed: 25176068
  • Ubil E  et al. Mesenchymal-endothelial transition contributes to cardiac neovascularization. Nature 514:585-90 (2014). Histology, Immunomicroscopy, IHC, Alexa Fluor® 680 ; Mouse . PubMed: 25317562
  • Newton VL  et al. Targeting apoptosis signalling kinase-1 (ASK-1) does not prevent the development of neuropathy in streptozotocin-induced diabetic mice. PLoS One 9:e107437 (2014). WB, IHC ; Mouse . PubMed: 25329046
  • Davaine JM  et al. Osteoprotegerin, pericytes and bone-like vascular calcification are associated with carotid plaque stability. PLoS One 9:e107642 (2014). IHC-P ; Human . PubMed: 25259713
  • Yang W  et al. Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells. J Cell Sci 126:4085-98 (2013). IHC ; Mouse . PubMed: 23843612
  • Hutchins NA  et al. Kupffer cells protect liver sinusoidal endothelial cells from Fas-dependent apoptosis in sepsis by down-regulating gp130. Am J Pathol 182:742-54 (2013). PubMed: 23306157
  • Rakian A  et al. Bone morphogenetic protein-2 gene controls tooth root development in coordination with formation of the periodontium. Int J Oral Sci 5:75-84 (2013). IHC . PubMed: 23807640
  • Nummela P  et al. Transforming growth factor beta-induced (TGFBI) is an anti-adhesive protein regulating the invasive growth of melanoma cells. Am J Pathol 180:1663-74 (2012). PubMed: 22326753
  • Liu WF  et al. CD146 expression correlates with epithelial-mesenchymal transition markers and a poor prognosis in gastric cancer. Int J Mol Sci 13:6399-406 (2012). PubMed: 22754372
  • Barclay GR  et al. Systematic assessment in an animal model of the angiogenic potential of different human cell sources for therapeutic revascularization. Stem Cell Res Ther 3:23 (2012). IHC-P . PubMed: 22759659
  • Yang W  et al. Bmp2 is required for odontoblast differentiation and pulp vasculogenesis. J Dent Res 91:58-64 (2012). Mouse . PubMed: 21984706
  • Bharadwaj S  et al. Characterization of urine-derived stem cells obtained from upper urinary tract for use in cell-based urological tissue engineering. Tissue Eng Part A 17:2123-32 (2011). ICC/IF ; Human . PubMed: 21513463
  • Sato A  et al. Establishment of a cell line from a Japanese patient useful for generating an in vivo model of malignant pleural mesothelioma. Cancer Sci 102:648-55 (2011). PubMed: 21205078
  • Sato A  et al. Immunocytochemistry of CD146 is useful to discriminate between malignant pleural mesothelioma and reactive mesothelium. Mod Pathol 23:1458-66 (2010). IHC (Methanol fixed) ; Human . PubMed: 20657552
  • Medic S & Ziman M PAX3 expression in normal skin melanocytes and melanocytic lesions (naevi and melanomas). PLoS One 5:e9977 (2010). IHC-P ; Human . PubMed: 20421967
  • Bodin A  et al. Tissue-engineered conduit using urine-derived stem cells seeded bacterial cellulose polymer in urinary reconstruction and diversion. Biomaterials 31:8889-901 (2010). ICC/IF ; Human . PubMed: 20800278


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