Overview

  • Product name
  • Description
    Rabbit polyclonal to CD168
  • Tested applications
    Suitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    A synthesized peptide derived from the internal region of Human CD168.

  • Positive control
    • Human breast carcinoma tissue; extracts from HepG2 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab110075 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 84 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function
    Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the focal adhesion kinase occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.
  • Tissue specificity
    Expressed in breast cancer cell lines and in normal breast tissue.
  • Cellular localization
    Cell surface. Cytoplasm.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD168 antibody
    • CD168 antigen antibody
    • HMMR antibody
    • HMMR_HUMAN antibody
    • Hyaluronan mediated motility receptor antibody
    • Hyaluronan-mediated motility receptor (RHAMM) antibody
    • IHABP antibody
    • Intracellular hyaluronic acid-binding protein antibody
    • MGC119494 antibody
    • MGC119495 antibody
    • OTTHUMP00000196920 antibody
    • Receptor for hyaluronan-mediated motility antibody
    • RHAMM antibody
    see all

Images

  • All lanes : Anti-CD168 antibody (ab110075) at 1/500 dilution

    Lane 1 : extracts from HepG2 cells
    Lane 2 : extracts from HepG2 cells with immunizing peptide at 10 µg

    Lysates/proteins at 30 µg per lane.


    Predicted band size : 84 kDa
  • Immunohistochemical analysis of paraffin embedded Human breast carcinoma tissue, using a 1/50 dilution ab110075 with (right image) or without (left image) the immunizing peptide.

References

ab110075 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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