The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application notesFlow Cyt: Use 10µl of the suggested working dilution to label 106 cells in 100µl.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Tissue specificityHighly expressed in normal bone marrow and weakly expressed in fetal liver. Expressed on neutrophils. Expressed in granulocytes of patients with polycythemia vera (PV) and with essential thrombocythemia (ET).
Sequence similaritiesContains 2 UPAR/Ly6 domains.
Post-translational modificationsN-glycosylated. A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding).