• Product nameAnti-CD19 (phospho Y531) antibody
    See all CD19 primary antibodies
  • Description
    Rabbit polyclonal to CD19 (phospho Y531)
  • Specificityab63443 detects CD19 only when phosphorylated at tyrosine 531.
  • Tested applicationsSuitable for: ELISA, WB, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse, Human
  • Immunogen

    Synthetic phosphopeptide derived from human CD19 around the phosphorylation site of tyrosine 531 (D-S-YP-E-N).

  • Positive control
    • COS7 cell extracts treated with Serum (10%, 30mins).



Our Abpromise guarantee covers the use of ab63443 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA 1/40000.
WB 1/500 - 1/1000. Detects a band of approximately 61 kDa (predicted molecular weight: 61 kDa).
Flow Cyt Use at an assay dependent concentration. PubMed: 20516366ab171870-Rabbit polyclonal IgG, is suitable for use as an isotype control with this antibody.


  • FunctionAssembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
  • Involvement in diseaseDefects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) [MIM:613493]; also called antibody deficiency due to CD19 defect. CVID3 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
  • Sequence similaritiesContains 2 Ig-like C2-type (immunoglobulin-like) domains.
  • Post-translational
    Phosphorylated on serine and threonine upon DNA damage, probably by ATM or ATR. Phosphorylated on tyrosine following B-cell activation.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antibody deficiency due to defect in CD19, included antibody
    • AW495831 antibody
    • B lymphocyte antigen CD19 antibody
    • B lymphocyte surface antigen B4 antibody
    • B-lymphocyte antigen CD19 antibody
    • B-lymphocyte surface antigen B4 antibody
    • B4 antibody
    • CD19 antibody
    • CD19 antigen antibody
    • CD19 molecule antibody
    • Cd19 protein antibody
    • CD19_HUMAN antibody
    • CVID3 antibody
    • Differentiation antigen CD19 antibody
    • Leu 12 antibody
    • Leu-12 antibody
    • Leu12 antibody
    • MGC109570 antibody
    • MGC12802 antibody
    • T-cell surface antigen Leu-12 antibody
    see all

Anti-CD19 (phospho Y531) antibody images

  • All lanes : Anti-CD19 (phospho Y531) antibody (ab63443) at 1/500 dilution

    Lane 1 : COS7 cell extracts (5-30µg total protein) treated with Serum (10%, 30mins)
    Lane 2 : COS7 cell extracts (5-30µg total protein) treated with Serum (10%, 30mins) with immunising peptide at 10 µg

    Predicted band size : 61 kDa
    Observed band size : 61 kDa

References for Anti-CD19 (phospho Y531) antibody (ab63443)

This product has been referenced in:
  • Séïté JF  et al. IVIg modulates BCR signaling through CD22 and promotes apoptosis in mature human B lymphocytes. Blood 116:1698-704 (2010). Flow Cyt ; Human . Read more (PubMed: 20516366) »

See 1 Publication for this product

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