Anti-CD1b+c antibody [B-B5] (ab27296)
- Datasheet
- Specific References (1)
- Protocols
Overview
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Product nameAnti-CD1b+c antibody [B-B5]
See all CD1b+c primary antibodies -
DescriptionMouse monoclonal [B-B5] to CD1b+c
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Host speciesMouse
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SpecificityThis antibody recognises CD1b+c proteins.
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Tested applicationsSuitable for: Flow Cytmore details
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Species reactivityReacts with: Human
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Immunogen
Thymus cells and Jurkat cell line.
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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Storage bufferPreservative: 0.1% Sodium Azide
Constituents: 1% BSA, PBS -
Concentration information loading... -
PurityIon Exchange Chromatography
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ClonalityMonoclonal
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Clone numberB-B5
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Myelomax63-Ag8.653
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IsotypeIgG1
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Research areas
Associated products
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Alternative Versions
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Compatible Secondaries
Applications
Our Abpromise guarantee covers the use of ab27296 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
Application notes
Flow Cyt: Use 10µl for 106 cells or 100µl of whole blood.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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RelevanceCD1B and CD1C are members of the CD1 family of major histocompatibility (MHC)-like glycoproteins. CD1 proteins mediate the presentation of lipid and glycolipid antigens to T cells. The CD1B protein localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. The human genome contains five CD1 family genes, clustered on chromosome 1. CD1 family members are thought to differ in their cellular localization and specificity for lipid ligands.
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Cellular localizationSingle-pass type I membrane protein.
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Database links
- Entrez Gene: 910 Human
- Entrez Gene: 911 Human
- Omim: 188340 Human
- Omim: 188360 Human
- SwissProt: P29016 Human
- SwissProt: P29017 Human
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Alternative names
- CD1 antibody
- CD1B antigen antibody
- CD1b molecule antibody
see all
Images
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![Flow Cytometry - Anti-CD1b+c antibody [B-B5] (ab27296)](http://a.abcam.com/ps/products/27/ab27296/Images/27296.gif)
Flow Cytometry - Anti-CD1b+c antibody [B-B5] (ab27296)A typical staining pattern with the B-B5 monoclonal antibody of Molt 4 cell line Ab27296, at a dilution of 10µl for 106 cells or 100 µl of whole blood, staining CD1b+c by Flow Cytometry.
Protocols
References
This product has been referenced in:
- Groot F et al. Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction. J Virol 79:3009-15 (2005). Read more (PubMed: 15709021) »
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"