Overview

  • Product nameAnti-CD1b+c antibody [B-B5]
    See all CD1b+c primary antibodies
  • Description
    Mouse monoclonal [B-B5] to CD1b+c
  • Tested applicationsFlow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Thymus cells and Jurkat cell line

  • Positive control
    • Molt 4 cell line

Properties

  • FormLiquid
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityIon Exchange Chromatography
  • Purification notesSterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free
  • Clonality Monoclonal
  • Clone numberB-B5
  • Myelomax63-Ag8.653
  • IsotypeIgG1
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab46863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent dilution.

Target

  • RelevanceCD1B and CD1C are members of the CD1 family of major histocompatibility (MHC)-like glycoproteins. CD1 proteins mediate the presentation of lipid and glycolipid antigens to T cells. The CD1B protein localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. The human genome contains five CD1 family genes, clustered on chromosome 1. CD1 family members are thought to differ in their cellular localization and specificity for lipid ligands.
  • Cellular localizationSingle-pass type I membrane protein.
  • Database links
  • Alternative names
    • CD1 antibody
    • CD1B antigen antibody
    • CD1b molecule antibody
    • CD1C antigen antibody
    • CD1c molecule antibody
    • R1 antibody
    • R7 antibody
    see all

Anti-CD1b+c antibody [B-B5] images

  • A typical staining pattern with ab46863 monoclonal antibody of Molt 4 cell line.

References for Anti-CD1b+c antibody [B-B5] (ab46863)

This product has been referenced in:
  • Groot F  et al. Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction. J Virol 79:3009-15 (2005). Read more (PubMed: 15709021) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"