Overview

  • Product name
    Anti-CD1d antibody [WTH1]
    See all CD1d primary antibodies
  • Description
    Mouse monoclonal [WTH1] to CD1d
  • Specificity
    ab119846 cross reacts weakly with Mouse tissue in IHC and WB, but reacts strongly with both Rat and Mouse antigens in FC and IP.
  • Tested applications
    Suitable for: WB, IP, ELISA, IHC-Fr, Functional Studies, Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Rat CD1d-transduced M12.4.1.C3 cells.

  • Positive control
    • LEW Rat spleen tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab119846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Use under non reducing condition. Detects a band of approximately 43-55 kDa (predicted molecular weight: 38 kDa).
IP Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration.
Flow Cyt Use 10µl for 106 cells. ab170191-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
  • Tissue specificity
    Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
  • Sequence similarities
    Contains 1 Ig-like (immunoglobulin-like) domain.
  • Cellular localization
    Cell membrane. Endosome membrane. Lysosome membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antigen-presenting glycoprotein CD1d antibody
    • CD1.1 antibody
    • CD1A antibody
    • CD1d antibody
    • CD1D antigen antibody
    • CD1D antigen d polypeptide antibody
    • CD1d molecule antibody
    • CD1D_HUMAN antibody
    • Cd1d1 antibody
    • differentiation antigen CD1 alpha 3 antibody
    • HMC class I antigen like glycoprotein CD1D antibody
    • Ly 38 antibody
    • MGC34622 antibody
    • R3 antibody
    • R3G1 antibody
    • T cell surface glycoprotein CD1d antibody
    • Thymocyte antigen CD1D antibody
    see all

Images

  • Immunoperoxidase staining of LEW Rat spleen follicle using ab119846.

References

This product has been referenced in:
  • Monzon-Casanova E CD1d expression in paneth cells and rat exocrine pancreas revealed by novel monoclonal antibodies which differentially affect NKT cell activation. PLoS One 5:13089 (2010). WB, Flow Cyt, Functional Studies, IHC-Fr, IP ; Mouse, Rat . Read more (PubMed: ) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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