Overview

  • Product name
    Anti-CD1d antibody [WTH1] (FITC)
    See all CD1d primary antibodies
  • Description
    Mouse monoclonal [WTH1] to CD1d (FITC)
  • Conjugation
    FITC. Ex: 493nm, Em: 528nm
  • Specificity
    Binds with high affinity to the mature CD1d heavy chain independently of beta-2-microglobulin.
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Mouse, Rat
  • Immunogen

    Rat CD1d-transduced M12.4.1.C3 cells.

  • Positive control
    • Rat thymocytes.
  • General notes


    Clone WTH1 efficiently blocks rat and mouse invariant natural killer T cell (iNKT cell) response to a-GalCer (an antigen for iNKT cells).

Properties

Applications

Our Abpromise guarantee covers the use of ab119897 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 10µl for 106 cells. in 100 µl.



ab91362-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
  • Tissue specificity
    Expressed on cortical thymocytes, on certain T-cell leukemias, and in various other tissues.
  • Sequence similarities
    Contains 1 Ig-like (immunoglobulin-like) domain.
  • Cellular localization
    Cell membrane. Endosome membrane. Lysosome membrane. Subject to intracellular trafficking between the cell membrane, endosomes and lysosomes.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antigen-presenting glycoprotein CD1d antibody
    • CD1.1 antibody
    • CD1A antibody
    • CD1d antibody
    • CD1D antigen antibody
    • CD1D antigen d polypeptide antibody
    • CD1d molecule antibody
    • CD1D_HUMAN antibody
    • Cd1d1 antibody
    • differentiation antigen CD1 alpha 3 antibody
    • HMC class I antigen like glycoprotein CD1D antibody
    • Ly 38 antibody
    • MGC34622 antibody
    • R3 antibody
    • R3G1 antibody
    • T cell surface glycoprotein CD1d antibody
    • Thymocyte antigen CD1D antibody
    see all

Images

  • Staining of rat thymocytes with ab119897 at 10µl X 106 cells.

References

This product has been referenced in:
  • Monzon-Casanova E  et al. CD1d expression in paneth cells and rat exocrine pancreas revealed by novel monoclonal antibodies which differentially affect NKT cell activation. PLoS One 5: (2010). Read more (PubMed: 20927351) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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