Overview

  • Product nameAnti-CD2 antibody
    See all CD2 primary antibodies
  • Description
    Rabbit polyclonal to CD2
  • SpecificityThis antibody reacts with the majority of T cells in peripheral lymphoid tissue, NK cells, cortical thymocytes and most malignant cells of T cell origin.
  • Tested applicationsSuitable for: WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment: KEITNALETW GALGQDINLD IPSFQMSDDI DDIKWEKTSD KKKIAQ FRK EKETFKE KD TYKLFKNGTL KIKHLKTDDQ DIYKVSIYDT KGKNVLEKIF DLKIQERV S KPKISWTCI NTTLTCEVMN GTDPELNLYQ DGKHLKLSQR VITHKWTTSL SAKFKCTAGN KVSKESSVEP VSCPEKGLD, corresponding to amino acids 25-209 of Human CD2

  • Positive control
    • Tonsil.

Properties

Applications

Our Abpromise guarantee covers the use of ab37212 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 55 kDa (predicted molecular weight: 39 kDa).
IHC-P 1/50. Incubate for 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 1mM EDTA, pH 8.0 for 10 min followed by cooling at RT for 20 min.

Target

  • FunctionCD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
  • Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 2 antibody
    • CD2 antibody
    • CD2 antigen (p50), sheep red blood cell receptor antibody
    • CD2 antigen antibody
    • CD2 molecule antibody
    • CD2_HUMAN antibody
    • Erythrocyte receptor antibody
    • FLJ46032 antibody
    • LFA-2 antibody
    • LFA-3 receptor antibody
    • LFA2 antibody
    • LFA3 receptor antibody
    • Ly-37 antibody
    • Lymphocyte function antigen 2 antibody
    • lymphocyte-function antigen-2 antibody
    • OTTHUMP00000024366 antibody
    • Rosette receptor antibody
    • Sheep erythrocyte receptor antibody
    • SRBC antibody
    • T cell surface antigen CD2 antibody
    • T-cell surface antigen CD2 antibody
    • T-cell surface antigen T11/Leu-5 antibody
    • T-lymphocyte surface CD2 antigen antibody
    • T11 antibody
    see all

Anti-CD2 antibody images

  • Ab37212 staining human CD2 in tonsil by immunohistochemistry, Formalin fixed Paraffin embedded tissue.
  • Anti-CD2 antibody (ab37212) at 1/25 dilution + Jurkat cell lysate

    Predicted band size : 39 kDa
    Observed band size : 55 kDa (why is the actual band size different from the predicted?)

References for Anti-CD2 antibody (ab37212)

This product has been referenced in:

See 1 Publication for this product

Product Wall

Thank you for your enquiry. As far as we are aware, cross reactivity with mouse has not yet been tested for use with ab37212. Therefore it is not known whether or not it cross reacts with mouse. I hope this information helps, please do not hesit...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"