Overview

  • Product name
    Anti-CD2 antibody [B-E2] (FITC)
    See all CD2 primary antibodies
  • Description
    Mouse monoclonal [B-E2] to CD2 (FITC)
  • Conjugation
    FITC. Ex: 493nm, Em: 528nm
  • Specificity
    Recognises the Lymphocyte Function associated Antigen-2 (LFA-2)
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human thymocytes

  • Positive control
    • Lymphocytes

Properties

Applications

Our Abpromise guarantee covers the use of ab27392 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notes
    Flow Cyt: Use 10µl for 106 cells or 100 µl of whole blood.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
    • Sequence similarities
      Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD 2 antibody
      • CD2 antibody
      • CD2 antigen (p50), sheep red blood cell receptor antibody
      • CD2 antigen antibody
      • CD2 molecule antibody
      • CD2_HUMAN antibody
      • Erythrocyte receptor antibody
      • FLJ46032 antibody
      • LFA-2 antibody
      • LFA-3 receptor antibody
      • LFA2 antibody
      • LFA3 receptor antibody
      • Ly-37 antibody
      • Lymphocyte function antigen 2 antibody
      • lymphocyte-function antigen-2 antibody
      • OTTHUMP00000024366 antibody
      • Rosette receptor antibody
      • Sheep erythrocyte receptor antibody
      • SRBC antibody
      • T cell surface antigen CD2 antibody
      • T-cell surface antigen CD2 antibody
      • T-cell surface antigen T11/Leu-5 antibody
      • T-lymphocyte surface CD2 antigen antibody
      • T11 antibody
      see all

    Images

    • A typical staining pattern with ab27392 of lymphocytes

    References

    This product has been referenced in:
    • Przepiorka D  et al. A phase II study of BTI-322, a monoclonal anti-CD2 antibody, for treatment of steroid-resistant acute graft-versus-host disease. Blood 92:4066-71 (1998). Read more (PubMed: 9834211) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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