Overview

  • Product nameAnti-CD2 antibody [LT2] (Biotin)
    See all CD2 primary antibodies
  • Description
    Mouse monoclonal [LT2] to CD2 (Biotin)
  • ConjugationBiotin
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human, Rhesus monkey
  • Immunogen

    Tissue/ cell preparation: Normal human peripheral blood lymphocytes.

  • Positive control
    • Human peripheral blood lymphocytes
  • General notes


    ab27994 inhibits NK cell mediated cytotoxicity, and ConA and PHA mediated blast transformation.

Properties

Applications

Our Abpromise guarantee covers the use of ab27994 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 10µl for 106 cells.

Use 10µl for 106 cells, or 100µl of whole blood.





ab18418-Mouse monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

Target

  • FunctionCD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
  • Sequence similaritiesContains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 2 antibody
    • CD2 antibody
    • CD2 antigen (p50), sheep red blood cell receptor antibody
    • CD2 antigen antibody
    • CD2 molecule antibody
    • CD2_HUMAN antibody
    • Erythrocyte receptor antibody
    • FLJ46032 antibody
    • LFA-2 antibody
    • LFA-3 receptor antibody
    • LFA2 antibody
    • LFA3 receptor antibody
    • Ly-37 antibody
    • Lymphocyte function antigen 2 antibody
    • lymphocyte-function antigen-2 antibody
    • OTTHUMP00000024366 antibody
    • Rosette receptor antibody
    • Sheep erythrocyte receptor antibody
    • SRBC antibody
    • T cell surface antigen CD2 antibody
    • T-cell surface antigen CD2 antibody
    • T-cell surface antigen T11/Leu-5 antibody
    • T-lymphocyte surface CD2 antigen antibody
    • T11 antibody
    see all

Anti-CD2 antibody [LT2] (Biotin) images

  • FACS analysis of CD2 expression in human peripheral blood lymphocytes using biotin conjugated ab27994 at 10µl for 106 cells.

References for Anti-CD2 antibody [LT2] (Biotin) (ab27994)

This product has been referenced in:
  • Lin CW  et al. CD94 1A transcripts characterize lymphoblastic lymphoma/leukemia of immature natural killer cell origin with distinct clinical features. Blood 106:3567-74 (2005). Read more (PubMed: 16046525) »
  • Beyers AD  et al. Activation of T lymphocytes via monoclonal antibodies against rat cell surface antigens with particular reference to CD2 antigen. Immunol Rev 111:59-77 (1989). Read more (PubMed: 2576418) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"