Overview

  • Product name
    Anti-CD2 antibody [RPA-2.10] (PE/Cy5®)
    See all CD2 primary antibodies
  • Description
    Mouse monoclonal [RPA-2.10] to CD2 (PE/Cy5®)
  • Conjugation
    PE/Cy5®. Ex: 496nm, Em: 670nm
  • Specificity
    RPA-2.10 blocks mixed lymphocyte reaction.
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human, Pig, Non human primates
  • Immunogen

    CD2 of human origin

  • Positive control
    • Normal human peripheral blood cells/leukocytes

Properties

Applications

Our Abpromise guarantee covers the use of ab95556 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 5µl for 106 cells. ab67435-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • Function
    CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
  • Sequence similarities
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 2 antibody
    • CD2 antibody
    • CD2 antigen (p50), sheep red blood cell receptor antibody
    • CD2 antigen antibody
    • CD2 molecule antibody
    • CD2_HUMAN antibody
    • Erythrocyte receptor antibody
    • FLJ46032 antibody
    • LFA-2 antibody
    • LFA-3 receptor antibody
    • LFA2 antibody
    • LFA3 receptor antibody
    • Ly-37 antibody
    • Lymphocyte function antigen 2 antibody
    • lymphocyte-function antigen-2 antibody
    • OTTHUMP00000024366 antibody
    • Rosette receptor antibody
    • Sheep erythrocyte receptor antibody
    • SRBC antibody
    • T cell surface antigen CD2 antibody
    • T-cell surface antigen CD2 antibody
    • T-cell surface antigen T11/Leu-5 antibody
    • T-lymphocyte surface CD2 antigen antibody
    • T11 antibody
    see all

Images

  • Flow cytometry staining of normal human peripheral blood cells with Mouse IgG1 ? Isotype Control PE-Cy5 (open histogram) or ab95556 (filled histogram). Total cells were used for analysis.

References

This product has been referenced in:
  • Kap YS  et al. A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates. J Histochem Cytochem 57:1159-67 (2009). Read more (PubMed: 19729671) »
  • Aversa GG  et al. RPA-2.10: an anti-CD2 monoclonal antibody that inhibits alloimmune responses and monitors T cell activation. Transplant Proc 19:277-8 (1987). Read more (PubMed: 2908548) »

See all 2 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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