Overview

  • Product nameAnti-CD20 antibody [BV11], prediluted
    See all CD20 primary antibodies
  • Description
    Rabbit monoclonal [BV11] to CD20, prediluted
  • Tested applicationsSuitable for: IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide from the C-terminus of human CD20 protein.

  • Positive control
    • Human tonsil.

Properties

Applications

Our Abpromise guarantee covers the use of ab73095 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P
IHC-Fr
  • Application notesIHC-P: Use neat for 30-60 minutes at room temperature.
    IHC-Fr (acetone-fixed): Use neat for 30-60 minutes at room temperature.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionThis protein may be involved in the regulation of B-cell activation and proliferation.
    • Tissue specificityExpressed on B-cells.
    • Involvement in diseaseDefects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5) [MIM:613495]; also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low.
    • Sequence similaritiesBelongs to the MS4A family.
    • Post-translational
      modifications
      Phosphorylated. Might be functionally regulated by protein kinase(s).
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • APY antibody
      • ATOPY antibody
      • B lymphocyte antigen CD20 antibody
      • B Lymphocyte Cell Surface Antigen B1 antibody
      • B-lymphocyte antigen CD20 antibody
      • B-lymphocyte cell-surface antigen B1 antibody
      • B-lymphocyte surface antigen B1 antibody
      • B1 antibody
      • Bp 35 antibody
      • Bp35 antibody
      • CD 20 antibody
      • CD20 antibody
      • CD20 antigen antibody
      • CD20 receptor antibody
      • CD20_HUMAN antibody
      • CVID5 antibody
      • Fc epsilon receptor I beta chain antibody
      • Fc Fragment of IgE high affinity I receptor for beta polypeptide antibody
      • FCER1B antibody
      • High affinity immunoglobulin epsilon receptor subunit beta antibody
      • IgE Fc receptor subunit beta antibody
      • IGEL antibody
      • IGER antibody
      • IGHER antibody
      • LEU 16 antibody
      • LEU16 antibody
      • leukocyte surface antigen Leu 16 antibody
      • Leukocyte surface antigen Leu-16 antibody
      • Ly44 antibody
      • Membrane spanning 4 domains A1 antibody
      • Membrane spanning 4 domains subfamily A member 2 antibody
      • Membrane-spanning 4-domains subfamily A member 1 antibody
      • MS4A1 antibody
      • MS4A2 antibody
      • S7 antibody
      see all

    Anti-CD20 antibody [BV11], prediluted images

    • ab73095 staining CD20 in human tonsils by Immunohistochemistry using formalin-fixed, paraffin-embedded tissue.

    References for Anti-CD20 antibody [BV11], prediluted (ab73095)

    This product has been referenced in:
    • Groot Kormelink T  et al. Immunoglobulin free light chains are increased in hypersensitivity pneumonitis and idiopathic pulmonary fibrosis. PLoS One 6:e25392 (2011). IHC-P ; Human . Read more (PubMed: 21980441) »
    • Kormelink TG  et al. Decrease in immunoglobulin free light chains in patients with rheumatoid arthritis upon rituximab (anti-CD20) treatment correlates with decrease in disease activity. Ann Rheum Dis 69:2137-44 (2010). Read more (PubMed: 20679475) »

    See all 2 Publications for this product

    Product Wall

    There are currently no Abreviews or Questions for ab73095.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"