Anti-CD21 antibody [1F8], prediluted (ab7290)


  • Product nameAnti-CD21 antibody [1F8], prediluted
    See all CD21 primary antibodies
  • Description
    Mouse monoclonal [1F8] to CD21, prediluted
  • SpecificityThis antibody reacts with CD21 antigen of MW 145 kD, present on the surface of mature B cells. The antigen is present at high density on follicular dendritic cells. CD21 is involved in transmitting growth-promoting signals to the interior of the B cell.
  • Tested applicationsSuitable for: IHC-P, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Purified receptor for the C3d fragment of the third complement component CR2, from human tonsil.

  • Positive control
    • Tonsil.


  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferConstituents: PBS
  • Concentration information loading...
  • PurityProtein A purified
  • ClonalityMonoclonal
  • Clone number1F8
  • IsotypeIgG1
  • Light chain typekappa
  • Research areas


Our Abpromise guarantee covers the use of ab7290 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
  • Application notesIHC-P: Use at an assay dependent dilution.
    IHC-Fr: Use at an assay dependent dilution.
    We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation should be determined by the user.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionReceptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.
    • Tissue specificityMature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.
    • Involvement in diseaseGenetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
    • Sequence similaritiesBelongs to the receptors of complement activation (RCA) family.
      Contains 15 Sushi (CCP/SCR) domains.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • C3DR antibody
      • CD 21 antibody
      • CD21 antibody
      • Complement C3d receptor antibody
      • Complement component (3d/Epstein Barr virus) receptor 2 antibody
      • Complement receptor type 2 antibody
      • CR antibody
      • Cr2 antibody
      • CR2_HUMAN antibody
      • CVID7 antibody
      • EBV receptor antibody
      • EBV-R antibody
      • Epstein Barr virus receptor antibody
      • Epstein-Barr virus receptor antibody
      • EVBR antibody
      • SLEB9 antibody
      see all

    References for Anti-CD21 antibody [1F8], prediluted (ab7290)

    ab7290 has not yet been referenced specifically in any publications.

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