Overview

  • Product nameAnti-CD21 antibody [B-E5]
    See all CD21 primary antibodies
  • Description
    Mouse monoclonal [B-E5] to CD21
  • SpecificityThis antibody is specific for CD21. (Recognises the soluble antigen).
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Daudi cell line

  • Positive control
    • human lymphocytes

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: None
    Constituents: PBS
  • Concentration information loading...
  • PurityIon Exchange Chromatography
  • Purification notesSterile-filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free.
  • ClonalityMonoclonal
  • Clone numberB-E5
  • Myelomax63-Ag8.653
  • IsotypeIgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab46900 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notesFlow Cyt: Use at an assay dependent dilution.
    Induces human B lymphocytes proliferation
    Competes with EBV for CD21 binding

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionReceptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.
    • Tissue specificityMature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.
    • Involvement in diseaseGenetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.
    • Sequence similaritiesBelongs to the receptors of complement activation (RCA) family.
      Contains 15 Sushi (CCP/SCR) domains.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • C3DR antibody
      • CD 21 antibody
      • CD21 antibody
      • Complement C3d receptor antibody
      • Complement component (3d/Epstein Barr virus) receptor 2 antibody
      • Complement receptor type 2 antibody
      • CR antibody
      • Cr2 antibody
      • CR2_HUMAN antibody
      • CVID7 antibody
      • EBV receptor antibody
      • EBV-R antibody
      • Epstein Barr virus receptor antibody
      • Epstein-Barr virus receptor antibody
      • EVBR antibody
      • SLEB9 antibody
      see all

    Anti-CD21 antibody [B-E5] images

    • A typical lymphocytes staining pattern with ab46900.

    References for Anti-CD21 antibody [B-E5] (ab46900)

    ab46900 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab46900.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"