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Product Name
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CD21 antibody [BB6-11C9.6] (FITC)
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See all CD21 antibodies (19)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [BB6-11C9.6] to CD21 (FITC)
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Immunogen
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The details of the immunogen for this antibody are not available.
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Reacts with
(species key)
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Pig
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Specificity
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ab24887 recognises Porcine CD21.
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Tested applications
(see key)
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Flow Cyt, IHC-Fr, IP
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Flow Cyt: Use 1µg for 106 cells.
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Type I membrane protein
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Research areas
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Immunology >> Adaptive Immunity >> B Cells >> CD
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Relevance
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CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.
ab24887 stains the following percentages of surface immunoglobulin (sIg) positive cells in porcine lymphoid tissues: 92-96% in peripheral blood; 74-98% in mesenteric lymph nodes; 97-100% in ileal Peyer’s patches (ILPP); 93-97% in spleen; and 0% in thymus. The antibody does not stain B cells in cord blood or spleen from pig fetuses (105 days gestation).
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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BB6-11C9.6
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Isotype
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IgG1
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Light chain type
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kappa
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Purity
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IgG fraction
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Storage buffer
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Preservative: 0.1% Sodium Azide
Constituents: PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Conjugation
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Fluorescein
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Concentration
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0.500 mg/ml
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Storage instructions
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Store at +4°C in the dark.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD21 antibody [BB6-11C9.6] (FITC) is on this datasheet. But please do contact us if you would like any reassurance! |
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References for CD21 antibody [BB6-11C9.6] (FITC) (ab24887)
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This clone has been used in:
Denham S et al. Monoclonal antibodies putatively identifying porcine B cells. Vet Immunol Immunopathol 60:317-28 (1998). PubMed: 9589570
If you publish research using ab24887 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to CD21
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CD21 antibody [BB6-11C9.6] (FITC) - more information
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