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Anti-CD21 antibody [BU32] (Phycoerythrin) (ab23771)

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Overview

Product name

Anti-CD21 antibody [BU32] (Phycoerythrin)
See all CD21 products (20) ...

Description

Mouse monoclonal [BU32] to CD21 (Phycoerythrin)

Conjugation

Phycoerythrin

Tested applications

IF, IHC-Fr, Flow Cytmore details

Cross reactivity

Reacts with

Human

Immunogen

Tissue / cell preparation (Human) - Purified human B cells from lymph node.

Properties

Form

Liquid

Storage instructions

Store at +4°C in the dark. Do not freeze.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: PBS, BSA

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Monoclonal

Clone number

BU32

Isotype

IgG1

Research areas

Immunology >> Adaptive Immunity >> B Cells >> CD

Applications

Show applications key

Our Abpromise guarantee covers the use of ab23771 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Function

Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.

Tissue specificity

Mature B-lymphocytes, T-lymphocytes, pharyngeal epithelial cells, astrocytes and follicular dendritic cells of the spleen.

Involvement in disease

Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9) [MIM:610927]. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system.

Sequence similarities

Belongs to the receptors of complement activation (RCA) family.
Contains 15 Sushi (CCP/SCR) domains.

Cellular localization

Membrane.

Target information above from: UniProt accessionP20023 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • C3DR antibody
  • CD 21 antibody
  • CD21 antibody
  • Complement C3d receptor antibody
  • Complement receptor type 2 antibody
  • Cr2 antibody
  • CR2_HUMAN antibody
  • EBV receptor antibody
  • Epstein Barr virus receptor antibody
  • Epstein-Barr virus receptor antibody
see all

References for Anti-CD21 antibody [BU32] (Phycoerythrin) (ab23771)

ab23771 has not yet been referenced specifically in any publications.

Publishing research using ab23771? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"