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Product Name
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CD21 antibody [LT21] (FITC)
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See all CD21 antibodies (19)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal [LT21] to CD21 (FITC)
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Immunogen
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IM9 human B-lymphoblastoid cell line.
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Reacts with
(species key)
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Hu, Cow, Pig
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Tested applications
(see key)
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Flow Cyt
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Abreviews
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Application notes
(see key)
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Recommended dilutions
Flow Cyt: Use 20µl for 106 cells or 100 µl of whole blood.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Type I membrane protein
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Research areas
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Immunology >> Adaptive Immunity >> B Cells >> CD
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Relevance
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CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kDa protein. CD21 is a glycosylated type I transmembrane protein consisting of an extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signalling pathways in human monocytes. By inducing release of proinflammatory cytokines and upregulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders.
CD21 is expressed on B lymphocytes, follicular dendritic cells, some epithelial cells and a subsets of T lymphocytes. It is not expressed on immature B cells.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Clone number
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LT21
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Isotype
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IgG1
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Purity
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Size exclusion
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Storage buffer
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Preservative: 15mM Sodium Azide
Constituents: 0.2% BSA, PBS Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Purification notes
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>95% pure (by SDS Page).
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Form
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Liquid
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Conjugation
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Fluorescein
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Storage instructions
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Store at +4°C in the dark. Do not freeze.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this CD21 antibody [LT21] (FITC) is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to CD21
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CD21 antibody [LT21] (FITC) - more information
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Customer reviews (feedback) regarding CD21 antibody [LT21] (FITC) |
Customer FAQs regarding CD21 antibody [LT21] (FITC) |
Protocols for CD21 antibody [LT21] (FITC) |
Price and availability of products related to CD21 antibody [LT21] (FITC) |
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CD21 antibody [LT21] (FITC) - related products:
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CD21 antibody [LT21] (FITC) - other tools:
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Contact Abcam with a Technical Enquiry about CD21 antibody [LT21] (FITC) |
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