Overview

  • Product nameAnti-CD239 antibody [EPR4164]
    See all CD239 primary antibodies
  • Description
    Rabbit monoclonal [EPR4164] to CD239
  • Tested applicationsSuitable for: IHC-P, ICCmore details
    Unsuitable for: Flow Cyt,IP or WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human CD239.

  • Positive control
    • Human Breast Carcinoma and Tonsil Tissues.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Properties

Applications

Our Abpromise guarantee covers the use of ab111181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
ICC 1/100 - 1/250.
  • Application notesIs unsuitable for Flow Cyt,IP or WB.
  • Target

    • FunctionLaminin alpha-5 receptor. May mediate intracellular signaling.
    • Tissue specificityWide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.
    • Sequence similaritiesContains 3 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 2 Ig-like V-type (immunoglobulin-like) domains.
    • Developmental stageIs under developmental control in liver and may also be regulated during differentiation in other tissues. Up-regulated following malignant transformation in some cell types.
    • Post-translational
      modifications
      Epinephrine-stimulated phosphorylation of Ser-621 by PKA enhances adhesion to laminin.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Antigen identified by monoclonal antibody F8 antibody
      • AU antibody
      • Auberger B antigen antibody
      • B CAM cell surface glycoprotein antibody
      • B cell adhesion molecule antibody
      • B-CAM cell surface glycoprotein antibody
      • Basal cell adhesion molecule (Lu and Au blood groups) antibody
      • Basal cell adhesion molecule (Lutheran blood group) antibody
      • Basal cell adhesion molecule antibody
      • Basal cell adhesion molecule Lu and Au blood groups antibody
      • Basal cell adhesion molecule Lutheran blood group antibody
      • Bcam antibody
      • BCAM_HUMAN antibody
      • CD239 antibody
      • CD239 antigen antibody
      • F8/G253 antigen antibody
      • Glycoprotein 95kDa antibody
      • LU antibody
      • Lutheran antibody
      • Lutheran antigen antibody
      • Lutheran blood group (Auberger b antigen included) antibody
      • Lutheran blood group Auberger b antigen included antibody
      • Lutheran blood group glycoprotein antibody
      • MSK19 antibody
      see all

    Anti-CD239 antibody [EPR4164] images

    • ab111181 at 1/100 dilution staining CD239 in Paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry.
    • ab111181 at 1/100 dilution staining CD239 in Paraffin-embedded Human tonsil tissue by Immunohistochemistry.
    • ab111181 showing positive staining in Thyroid gland carcinoma tissue.

    • ab111181 showing positive staining in Normal stomach tissue.

    • ab111181 showing positive staining in Normal ovary tissue.

    • ab111181 showing positive staining in Normal liver tissue.

    • ab111181 showing positive staining in Normal kidney tissue.

    • ab111181 showing positive staining in Hepatocellular carcinoma tissue.

    • ab111181 showing negative staining in Normal heart tissue.

    References for Anti-CD239 antibody [EPR4164] (ab111181)

    ab111181 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab111181.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"