Recombinant
RabMAb

Anti-CD239 antibody [EPR4164] (ab111181)

Overview

  • Product name
    Anti-CD239 antibody [EPR4164]
    See all CD239 primary antibodies
  • Description
    Rabbit monoclonal [EPR4164] to CD239
  • Tested applications
    Suitable for: IHC-P, ICCmore details
    Unsuitable for: Flow Cyt,IP or WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human CD239.

  • Positive control
    • Human Breast Carcinoma and Tonsil Tissues.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

Applications

Our Abpromise guarantee covers the use of ab111181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/100 - 1/250. Perform heat mediated antigen retrieval via the pressure cooker method before commencing with IHC staining protocol.
ICC 1/100 - 1/250.
  • Application notes
    Is unsuitable for Flow Cyt,IP or WB.
  • Target

    • Function
      Laminin alpha-5 receptor. May mediate intracellular signaling.
    • Tissue specificity
      Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.
    • Sequence similarities
      Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
      Contains 2 Ig-like V-type (immunoglobulin-like) domains.
    • Developmental stage
      Is under developmental control in liver and may also be regulated during differentiation in other tissues. Up-regulated following malignant transformation in some cell types.
    • Post-translational
      modifications
      Epinephrine-stimulated phosphorylation of Ser-621 by PKA enhances adhesion to laminin.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • Antigen identified by monoclonal antibody F8 antibody
      • AU antibody
      • Auberger B antigen antibody
      • B CAM cell surface glycoprotein antibody
      • B cell adhesion molecule antibody
      • B-CAM cell surface glycoprotein antibody
      • Basal cell adhesion molecule (Lu and Au blood groups) antibody
      • Basal cell adhesion molecule (Lutheran blood group) antibody
      • Basal cell adhesion molecule antibody
      • Basal cell adhesion molecule Lu and Au blood groups antibody
      • Basal cell adhesion molecule Lutheran blood group antibody
      • Bcam antibody
      • BCAM_HUMAN antibody
      • CD239 antibody
      • CD239 antigen antibody
      • F8/G253 antigen antibody
      • Glycoprotein 95kDa antibody
      • LU antibody
      • Lutheran antibody
      • Lutheran antigen antibody
      • Lutheran blood group (Auberger b antigen included) antibody
      • Lutheran blood group Auberger b antigen included antibody
      • Lutheran blood group glycoprotein antibody
      • MSK19 antibody
      see all

    Images

    • ab111181 at 1/100 dilution staining CD239 in Paraffin-embedded Human breast carcinoma tissue by Immunohistochemistry.
    • ab111181 at 1/100 dilution staining CD239 in Paraffin-embedded Human tonsil tissue by Immunohistochemistry.
    • ab111181 showing positive staining in Thyroid gland carcinoma tissue.

    • ab111181 showing positive staining in Normal stomach tissue.

    • ab111181 showing positive staining in Normal ovary tissue.

    • ab111181 showing positive staining in Normal liver tissue.

    • ab111181 showing positive staining in Normal kidney tissue.

    • ab111181 showing positive staining in Hepatocellular carcinoma tissue.

    • ab111181 showing negative staining in Normal heart tissue.

    References

    ab111181 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab111181.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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