Anti-CD239 antibody [MM0107-1M39] (ab89142)

Overview

  • Product name
    Anti-CD239 antibody [MM0107-1M39]
    See all CD239 primary antibodies
  • Description
    Mouse monoclonal [MM0107-1M39] to CD239
  • Tested applications
    Suitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Recombinant fragment (Human) - extracellular region

Properties

Applications

Our Abpromise guarantee covers the use of ab89142 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 67 kDa.

Target

  • Function
    Laminin alpha-5 receptor. May mediate intracellular signaling.
  • Tissue specificity
    Wide tissue distribution (highest in the pancreas and very low in brain). Closely associated with the basal layer of cells in epithelia and the endothelium of blood vessel walls.
  • Sequence similarities
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 2 Ig-like V-type (immunoglobulin-like) domains.
  • Developmental stage
    Is under developmental control in liver and may also be regulated during differentiation in other tissues. Up-regulated following malignant transformation in some cell types.
  • Post-translational
    modifications
    Epinephrine-stimulated phosphorylation of Ser-621 by PKA enhances adhesion to laminin.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antigen identified by monoclonal antibody F8 antibody
    • AU antibody
    • Auberger B antigen antibody
    • B CAM cell surface glycoprotein antibody
    • B cell adhesion molecule antibody
    • B-CAM cell surface glycoprotein antibody
    • Basal cell adhesion molecule (Lu and Au blood groups) antibody
    • Basal cell adhesion molecule (Lutheran blood group) antibody
    • Basal cell adhesion molecule antibody
    • Basal cell adhesion molecule Lu and Au blood groups antibody
    • Basal cell adhesion molecule Lutheran blood group antibody
    • Bcam antibody
    • BCAM_HUMAN antibody
    • CD239 antibody
    • CD239 antigen antibody
    • F8/G253 antigen antibody
    • Glycoprotein 95kDa antibody
    • LU antibody
    • Lutheran antibody
    • Lutheran antigen antibody
    • Lutheran blood group (Auberger b antigen included) antibody
    • Lutheran blood group Auberger b antigen included antibody
    • Lutheran blood group glycoprotein antibody
    • MSK19 antibody
    see all

Images

  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human placental tissue section (4µm) labelling CD239 with ab89142. Tissue was treated with 15µg/ml Protenase K for antigen retrieval and fixed with 4% PFA. A HRP-conjugated anti-mouse IgG was used as the secondary antibody (30 minutes at room temperature) followed by DAB color development.

References

ab89142 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Expiration date: June 29th, 2012
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To our knowledge, ab89142 has not been tested in FC. We do not have trial sizes of our products as we carry over 70,000 items and can't store multiple vial sizes in our automated freezers. Th...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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