Overview

  • Product nameAnti-CD244 antibody [2B4.69]See all CD244 primary antibodies ...
  • Description
    Mouse monoclonal [2B4.69] to CD244
  • Specificityab54254 is specific for the CD244 cell surface antigen, also known as natural killer receptor 2B4 (NKG2B4).
  • Tested applicationsIP, Flow Cyt more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    CD244 Fusion protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab54254 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
IP
Flow Cyt
  • Application notesFlow Cyt: 1/50 - 1/200.
    Use 10ul of the suggested working dilution to label 1x106 cells in 100ul.
    IP: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • FunctionModulate other receptor-ligand interactions to enhance leukocyte activation.
    • Tissue specificityExpressed in spleen, PBL, followed by lung, liver, testis and small intestine. Expressed not only in NK cells, but also on monocytes and basophils.
    • Sequence similaritiesContains 2 Ig-like (immunoglobulin-like) domains.
    • Cellular localizationMembrane.
    • Target information above from: UniProt accession Q9BZW8 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
    • Alternative names
      • 2B4 antibody
      • C9.1 antibody
      • CD244 antibody
      • CD244 antigen antibody
      • CD244 molecule natural killer cell receptor 2B4 antibody
      • CD244 natural killer cell receptor 2B4 antibody
      • CD244_HUMAN antibody
      • F730046O15Rik antibody
      • h2B4 antibody
      • Ly90 antibody
      • NAIL antibody
      • Natural killer cell activation-inducing ligand antibody
      • Natural killer cell receptor 2B4 antibody
      • NK cell activation inducing ligand antibody
      • NK cell activation inducing ligand NAIL antibody
      • NK cell activation-inducing ligand antibody
      • NK cell type I receptor protein 2B4 antibody
      • NKR2B4 antibody
      • Nmrk antibody
      • Non-MHC restricted killing associated antibody
      • OTTHUMP00000027884 antibody
      • p38 antibody
      • signaling lymphocytic activation molecule 4 antibody
      • SLAM family, member 4 antibody
      • SLAMF4 antibody
      see all

    References for Anti-CD244 antibody [2B4.69] (ab54254)

    This product has been referenced in:
    • Ghio M  et al. Soluble HLA-I-mediated secretion of TGF-beta1 by human NK cells and consequent down-regulation of anti-tumor cytolytic activity. Eur J Immunol 39:3459-68 (2009). Flow Cyt ; Human . Read more (PubMed: 19830740) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"