Overview

  • Product nameAnti-CD252 antibody
    See all CD252 primary antibodies
  • Description
    Rabbit polyclonal to CD252
  • Tested applicationsSuitable for: WBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within internal amino acids 111-160 (

    QEVNISLHYQKDEEPLFQLKKVRSVNSLMVASLTYKDKVYLNVTTDNTSL

    ) of human CD252 (NP_003317).

  • Positive control
    • 293T cell lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab108083 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 21 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionCytokine that binds to TNFRSF4. Co-stimulates T-cell proliferation and cytokine production.
  • Involvement in diseaseGenetic variations in TNFSF4 influence susceptibility to systemic lupus erythematosus (SLE) [MIM:152700]. SLE is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue. It affects principally the skin, joints, kidneys and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. Note=The upstream region of TNFSF4 contains a single risk haplotype for SLE, which is correlated with increased expression of both cell-surface TNFSF4 and TNFSF4 transcripts. Increased levels of TNFSF4 are thought to augment T cell-APC interaction and the functional consequences of T cell activation, thereby destabilizing peripheral tolerance.
  • Sequence similaritiesBelongs to the tumor necrosis factor family.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 134L antibody
    • CD 252 antibody
    • CD134 antibody
    • CD134 ligand antibody
    • CD134L antibody
    • CD252 antibody
    • CD252 antigen antibody
    • glycoprotein 34 kd antibody
    • Glycoprotein Gp34 antibody
    • GP34 antibody
    • OX-40L antibody
    • OX40 antigen ligand antibody
    • OX40 ligand antibody
    • OX40L antibody
    • TAX transcriptionally-activated glycoprotein 1 antibody
    • TNFL4_HUMAN antibody
    • Tnfsf4 antibody
    • Tumor necrosis factor (ligand) superfamily member 4 antibody
    • Tumor necrosis factor ligand superfamily member 4 antibody
    • TXGP1 antibody
    see all

Anti-CD252 antibody images

  • Anti-CD252 antibody (ab108083) at 1 µg/ml + 293T cell lysate at 10 µg

    Predicted band size : 21 kDa

References for Anti-CD252 antibody (ab108083)

ab108083 has not yet been referenced specifically in any publications.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"