Overview

  • Product name
    Anti-CD28 antibody [CD28.2] (PerCP)
    See all CD28 primary antibodies
  • Description
    Mouse monoclonal [CD28.2] to CD28 (PerCP)
  • Conjugation
    PerCP. Ex: 482nm, Em: 675nm
  • Specificity
    Reacts with CD28, a disulfide-linked homodimeric type I glycoprotein (monomer of Mw 44 kDa) which is a critical costimulatory receptor of T cells.
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
    Predicted to work with: Non human primates
  • Immunogen

    DC28.1.3.3 hybridoma cells

  • Positive control
    • Human blood cells
  • General notes

    The purified antibody (>95% by SDS-PAGE) is conjugated with Peridinin-chlorophyll-protein complex (PerCP) under optimum conditions.

Properties

Applications

Our Abpromise guarantee covers the use of ab88034 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 10µl for 106 cells. ab118658-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • Function
    Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
  • Tissue specificity
    Expressed in T-cells and plasma cells, but not in less mature B-cells.
  • Sequence similarities
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 28 antibody
    • CD28 antibody
    • CD28 antigen antibody
    • CD28 molecule antibody
    • CD28_HUMAN antibody
    • MGC138290 antibody
    • T cell antigen CD28 antibody
    • T cell specific surface glycoprotein antibody
    • T cell specific surface glycoprotein CD28 antibody
    • T-cell-specific surface glycoprotein CD28 antibody
    • TP44 antibody
    see all

References

This product has been referenced in:
  • Scharschmidt E  et al. Degradation of Bcl10 induced by T-cell activation negatively regulates NF-kappa B signaling. Mol Cell Biol 24:3860-73 (2004). Read more (PubMed: 15082780) »
  • Jeong SH  et al. Immunization with hepatitis C virus-like particles induces humoral and cellular immune responses in nonhuman primates. J Virol 78:6995-7003 (2004). Read more (PubMed: 15194776) »

See all 7 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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