Overview

  • Product name
    Anti-CD28 antibody [JJ319]
    See all CD28 primary antibodies
  • Description
    Mouse monoclonal [JJ319] to CD28
  • Tested applications
    Suitable for: Flow Cyt, IP, Functional Studiesmore details
  • Species reactivity
    Reacts with: Rat
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notes


    Clone JJ319 has been identified as a highly effective co stimulator of T cell proliferation and IL2 secretion by resting T cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab35024 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt 1/50 - 1/100.

Use 10µl of the suggested working dilution to label 106 cells in 100µl.





ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration.

Target

  • Function
    Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
  • Tissue specificity
    Expressed in T-cells and plasma cells, but not in less mature B-cells.
  • Sequence similarities
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 28 antibody
    • CD28 antibody
    • CD28 antigen antibody
    • CD28 molecule antibody
    • CD28_HUMAN antibody
    • MGC138290 antibody
    • T cell antigen CD28 antibody
    • T cell specific surface glycoprotein antibody
    • T cell specific surface glycoprotein CD28 antibody
    • T-cell-specific surface glycoprotein CD28 antibody
    • TP44 antibody
    see all

References

This product has been referenced in:
  • Tacke M  et al. Cellular distribution and costimulatory function of rat CD28. Regulated expression during thymocyte maturation and induction of cyclosporin A sensitivity of costimulated T cell responses by phorbol ester. J Immunol 154:5121-7 (1995). Read more (PubMed: 7730618) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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