Anti-CD3 epsilon antibody [C363.29B (YCD3-1)] (Biotin) (ab25688)

Overview

  • Product name
    Anti-CD3 epsilon antibody [C363.29B (YCD3-1)] (Biotin)
    See all CD3 epsilon primary antibodies
  • Description
    Rat monoclonal [C363.29B (YCD3-1)] to CD3 epsilon (Biotin)
  • Conjugation
    Biotin
  • Specificity
    In the presence of Fc receptor bearing accessory cells, this antibody can activate primed and naïve T cell in vitro. When immobilized it can also activate both normal T lymphocytes and cloned T cell lines provided the appropriate accessory signals are present.
  • Tested applications
    Suitable for: Flow Cyt, IPmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Epitope
    This antibody recognises an epitope on the 25kDa epsilon chain of the CD3/TCR complex.

Properties

Applications

Our Abpromise guarantee covers the use of ab25688 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
IP
  • Application notes
    Flow Cyt: Use 3µg for 106 cells.
    IP: Use at an assay dependent dilution.
    In vitro depletion of CD3+ cells: Use at an assay dependent dilution.
    In vitro activation of T cells (accessory cells must be provided): Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      The CD3 complex mediates signal transduction.
    • Sequence similarities
      Contains 1 Ig-like (immunoglobulin-like) domain.
      Contains 1 ITAM domain.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD3 epsilon antibody
      • CD3e antibody
      • CD3e antigen epsilon polypeptide (TiT3 complex) antibody
      • CD3E antigen epsilon polypeptide antibody
      • CD3E antigen, epsilon subunit antibody
      • CD3e molecule epsilon antibody
      • CD3e molecule, epsilon (CD3 TCR complex) antibody
      • CD3e molecule, epsilon (CD3-TCR complex) antibody
      • CD3E_HUMAN antibody
      • IMD18 antibody
      • T cell antigen receptor complex epsilon subunit of T3 antibody
      • T cell surface antigen T3/Leu 4 epsilon chain antibody
      • T cell surface glycoprotein CD3 epsilon chain antibody
      • T-cell surface antigen T3/Leu-4 epsilon chain antibody
      • T-cell surface glycoprotein CD3 epsilon chain antibody
      • T3E antibody
      • TCRE antibody
      see all

    References for Anti-CD3 epsilon antibody [C363.29B (YCD3-1)] (Biotin) (ab25688)

    ab25688 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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