Overview

  • Product name
    Anti-CD30 antibody [CON6D/B5]
    See all CD30 primary antibodies
  • Description
    Mouse monoclonal [CON6D/B5] to CD30
  • Tested applications
    Suitable for: IHC-P, ICC/IF, IHC-Fr, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Hodgkin's lymphoma cell line L428 .

  • Positive control
    • Hodgkin's lymphoma tissue or L428 cell line

Properties

Applications

Our Abpromise guarantee covers the use of ab23766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use at an assay dependent concentration. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC/IF 1/30.
IHC-Fr Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.

Target

  • Function
    Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF-kappa-B.
  • Sequence similarities
    Contains 6 TNFR-Cys repeats.
  • Post-translational
    modifications
    Phosphorylated on serine and tyrosine residues.
  • Cellular localization
    Cytoplasm and Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 30 antibody
    • CD30 antibody
    • CD30 antigen antibody
    • CD30L receptor antibody
    • Cytokine receptor CD30 antibody
    • D1S166E antibody
    • KI 1 antibody
    • KI 1 antigen antibody
    • Ki-1 antigen antibody
    • KI1 antibody
    • Lymphocyte activation antigen CD30 antibody
    • TNFRSF 8 antibody
    • Tnfrsf8 antibody
    • TNR8_HUMAN antibody
    • Tumor necrosis factor receptor superfamily member 8 antibody
    see all

Images

  • CD30 - ab23766- Human Hodgkin's lymphoma. Formalin fixed, paraffin processed tissue.

  • Tissue: Hodgkin's Lymphoma
    ab23766 diluted 1:30

References

This product has been referenced in:
  • Lu TX  et al. Epstein-Barr virus positive diffuse large B-cell lymphoma predict poor outcome, regardless of the age. Sci Rep 5:12168 (2015). IHC ; Human . Read more (PubMed: 26202875) »
  • Mattsson G  et al. Detection of genetic alterations by immunoFISH analysis of whole cells extracted from routine biopsy material. J Mol Diagn 9:479-89 (2007). Read more (PubMed: 17690217) »

See all 3 Publications for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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