Recombinant
RabMAb

Anti-CD300 antigen antibody [EPR5226] (ab124810)

Overview

  • Product name
    Anti-CD300 antigen antibody [EPR5226]
    See all CD300 antigen primary antibodies
  • Description
    Rabbit monoclonal [EPR5226] to CD300 antigen
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human CD300 antigen.

  • Positive control
    • Human lymph node and spleen lysates.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab124810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 60 kDa (predicted molecular weight: 33 kDa).
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function
      Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
    • Tissue specificity
      Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.
    • Sequence similarities
      Belongs to the CD300 family.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Post-translational
      modifications
      Phosphorylated on tyrosine.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD300 antigen-like family member A antibody
      • CD300a antibody
      • CD300a antigen antibody
      • CD300a molecule antibody
      • CLM-8 antibody
      • CLM8_HUMAN antibody
      • CMRF 35 H9 antibody
      • CMRF-35-H9 antibody
      • CMRF35-H antibody
      • CMRF35-H9 antibody
      • CMRF35-like molecule 8 antibody
      • CMRF35H antibody
      • CMRF35H leukocyte immunoglobulin like receptor antibody
      • CMRF35H9 antibody
      • IgSF12 antibody
      • Immunoglobulin superfamily member 12 antibody
      • Inhibitory receptor protein 60 antibody
      • IRC1 antibody
      • IRC1/IRC2 antibody
      • IRC2 antibody
      • IRp60 antibody
      • Leukocyte membrane antigen antibody
      • Mast cell derived paired immunoglobulin like receptor 1 antibody
      • NK inhibitory receptor antibody
      • Polymeric immunoglobulin receptor 4 antibody
      see all

    Images

    • All lanes : Anti-CD300 antigen antibody [EPR5226] (ab124810) at 1/1000 dilution

      Lane 1 : Human lymph node lysates
      Lane 2 : Human spleen lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size: 33 kDa
      Observed band size: 60 kDa (why is the actual band size different from the predicted?)

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    ab124810 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab124810.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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