Anti-CD300 antigen antibody [EPR5226] (ab124810)

Overview

  • Product nameAnti-CD300 antigen antibody [EPR5226]
    See all CD300 antigen primary antibodies
  • Description
    Rabbit monoclonal [EPR5226] to CD300 antigen
  • Tested applicationsSuitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in Human CD300 antigen.

  • Positive control
    • Human lymph node and spleen lysates.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab124810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 60 kDa (predicted molecular weight: 33 kDa).
  • Application notesIs unsuitable for ICC,IHC-P or IP.
  • Target

    • FunctionInhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
    • Tissue specificityExpressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.
    • Sequence similaritiesBelongs to the CD300 family.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Post-translational
      modifications
      Phosphorylated on tyrosine.
    • Cellular localizationCell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD300 antigen-like family member A antibody
      • CD300a antibody
      • CD300a antigen antibody
      • CD300a molecule antibody
      • CLM-8 antibody
      • CLM8_HUMAN antibody
      • CMRF 35 H9 antibody
      • CMRF-35-H9 antibody
      • CMRF35-H antibody
      • CMRF35-H9 antibody
      • CMRF35-like molecule 8 antibody
      • CMRF35H antibody
      • CMRF35H leukocyte immunoglobulin like receptor antibody
      • CMRF35H9 antibody
      • IgSF12 antibody
      • Immunoglobulin superfamily member 12 antibody
      • Inhibitory receptor protein 60 antibody
      • IRC1 antibody
      • IRC1/IRC2 antibody
      • IRC2 antibody
      • IRp60 antibody
      • Leukocyte membrane antigen antibody
      • Mast cell derived paired immunoglobulin like receptor 1 antibody
      • NK inhibitory receptor antibody
      • Polymeric immunoglobulin receptor 4 antibody
      see all

    Anti-CD300 antigen antibody [EPR5226] images

    • All lanes : Anti-CD300 antigen antibody [EPR5226] (ab124810) at 1/1000 dilution

      Lane 1 : Human lymph node lysates
      Lane 2 : Human spleen lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size : 33 kDa
      Observed band size : 60 kDa (why is the actual band size different from the predicted?)
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References for Anti-CD300 antigen antibody [EPR5226] (ab124810)

    ab124810 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"