Recombinant
RabMAb

Anti-CD300 antigen antibody [EPR5226] (ab124810)

Overview

  • Product name
    Anti-CD300 antigen antibody [EPR5226]
    See all CD300 antigen primary antibodies
  • Description
    Rabbit monoclonal [EPR5226] to CD300 antigen
  • Host species
    Rabbit
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human CD300 antigen aa 50-150. The exact sequence is proprietary.

  • Positive control
    • Human lymph node and spleen lysates.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

    We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab124810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 60 kDa (predicted molecular weight: 33 kDa).
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function
      Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
    • Tissue specificity
      Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.
    • Sequence similarities
      Belongs to the CD300 family.
      Contains 1 Ig-like V-type (immunoglobulin-like) domain.
    • Post-translational
      modifications
      Phosphorylated on tyrosine.
    • Cellular localization
      Cell membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD300 antigen-like family member A antibody
      • CD300a antibody
      • CD300a antigen antibody
      • CD300a molecule antibody
      • CLM-8 antibody
      • CLM8_HUMAN antibody
      • CMRF 35 H9 antibody
      • CMRF-35-H9 antibody
      • CMRF35-H antibody
      • CMRF35-H9 antibody
      • CMRF35-like molecule 8 antibody
      • CMRF35H antibody
      • CMRF35H leukocyte immunoglobulin like receptor antibody
      • CMRF35H9 antibody
      • IgSF12 antibody
      • Immunoglobulin superfamily member 12 antibody
      • Inhibitory receptor protein 60 antibody
      • IRC1 antibody
      • IRC1/IRC2 antibody
      • IRC2 antibody
      • IRp60 antibody
      • Leukocyte membrane antigen antibody
      • Mast cell derived paired immunoglobulin like receptor 1 antibody
      • NK inhibitory receptor antibody
      • Polymeric immunoglobulin receptor 4 antibody
      see all

    Images

    • All lanes : Anti-CD300 antigen antibody [EPR5226] (ab124810) at 1/1000 dilution

      Lane 1 : Human lymph node lysates
      Lane 2 : Human spleen lysates

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Goat anti-Rabbit HRP at 1/2000 dilution

      Predicted band size: 33 kDa
      Observed band size: 60 kDa (why is the actual band size different from the predicted?)

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    ab124810 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab124810.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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