Overview

  • Product nameAnti-CD34 antibody [581] (PerCP)
    See all CD34 primary antibodies
  • Description
    Mouse monoclonal [581] to CD34 (PerCP)
  • ConjugationPerCP. Ex: 482nm, Em: 675nm
  • Specificityab119840 recognizes the class III CD34 epitope resistant to neuraminidase, chymopapain and glycoprotease.
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human, Non Human Primates
  • Immunogen

    Human CD34

  • Positive control
    • Human blood cells.

Applications

Our Abpromise guarantee covers the use of ab119840 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 10µl for 106 cells. ab118658-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • FunctionPossible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
  • Tissue specificitySelectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
  • Sequence similaritiesBelongs to the CD34 family.
  • Developmental stageOn early hematopoietic progenitor cells.
  • Post-translational
    modifications
    Highly glycosylated.
    Phosphorylated on serine residues by PKC.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD34 antibody
    • CD34 antigen antibody
    • CD34 molecule antibody
    • CD34_HUMAN antibody
    • Cluster designation 34 antibody
    • Hematopoietic progenitor cell antigen CD34 antibody
    • HPCA1 antibody
    • Mucosialin antibody
    • OTTHUMP00000034733 antibody
    • OTTHUMP00000034734 antibody
    see all

References for Anti-CD34 antibody [581] (PerCP) (ab119840)

This product has been referenced in:
  • Ono F  et al. CD34+ cells in the peripheral blood transport herpes simplex virus DNA fragments to the skin of patients with erythema multiforme (HAEM). J Invest Dermatol 124:1215-24 (2005). Read more (PubMed: 15955097) »
  • Felschow DM  et al. The adapter protein CrkL associates with CD34. Blood 97:3768-75 (2001). Read more (PubMed: 11389015) »

See all 3 Publications for this product

Product Wall

There are currently no Abreviews or Questions for ab119840.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"