Overview

  • Product name
    Anti-CD34 antibody [ICH-3] (Biotin)
    See all CD34 primary antibodies
  • Description
    Mouse monoclonal [ICH-3] to CD34 (Biotin)
  • Conjugation
    Biotin
  • Specificity
    The antibody recognizes the CD34 antigen, some cross reactions with vascular associated adventitia and some basement membranes.
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue/ cell preparation containing human CD34 protein.

Properties

Applications

Our Abpromise guarantee covers the use of ab34483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notes
    Flow Cyt: Use at a maximum of 1 µg of reagent for 106 cells.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins.
    • Tissue specificity
      Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues.
    • Sequence similarities
      Belongs to the CD34 family.
    • Developmental stage
      On early hematopoietic progenitor cells.
    • Post-translational
      modifications
      Highly glycosylated.
      Phosphorylated on serine residues by PKC.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD34 antibody
      • CD34 antigen antibody
      • CD34 molecule antibody
      • CD34_HUMAN antibody
      • Cluster designation 34 antibody
      • Hematopoietic progenitor cell antigen CD34 antibody
      • HPCA1 antibody
      • Mucosialin antibody
      • OTTHUMP00000034733 antibody
      • OTTHUMP00000034734 antibody
      see all

    References

    This product has been referenced in:
    • Berenson RJ  et al. Antigen CD34+ marrow cells engraft lethally irradiated baboons. J Clin Invest 81:951-5 (1988). Read more (PubMed: 2893812) »
    • Watt SM  et al. Distribution and epitope analysis of the cell membrane glycoprotein (HPCA-1) associated with human hemopoietic progenitor cells. Leukemia 1:417-26 (1987). Read more (PubMed: 2444831) »

    See all 3 Publications for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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