PE Anti-CD39 antibody [A1] (ab30424)
Key features and details
- PE Mouse monoclonal [A1] to CD39
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: PE. Ex: 488nm, Em: 575nm
- Isotype: IgG1
Related conjugates and formulations
Overview
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Product name
PE Anti-CD39 antibody [A1]
See all CD39 primary antibodies -
Description
PE Mouse monoclonal [A1] to CD39 -
Host species
Mouse -
Conjugation
PE. Ex: 488nm, Em: 575nm -
Specificity
Binds to the human CD39 cell surface antigen (70-100kD) -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Tissue, cells or virus corresponding to Human CD39. PHA activated human lymphocytes.
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General notes
CD39 has intrinsic ecto-ATPase activity.
Purified IgG conjugated to R. Phycoerythrin (RPE).
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.40
Preservative: 0.09% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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Purity
Protein G purified -
Purification notes
Protein G affinity chromatography from tissue culture supernatant. -
Primary antibody notes
CD39 has intrinsic ecto-ATPase activity. -
Clonality
Monoclonal -
Clone number
A1 -
Myeloma
NS1 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab30424 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
Use 10ul to label 10^6 cells or 100ul whole blood. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Notes |
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Flow Cyt
Use at an assay dependent concentration. Use 10ul to label 10^6 cells or 100ul whole blood. ab91357 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
Target
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Function
In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well. -
Tissue specificity
Expressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only. -
Sequence similarities
Belongs to the GDA1/CD39 NTPase family. -
Post-translational
modificationsThe N-terminus is blocked.
Palmitoylated in the N-terminal part. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 953 Human
- Omim: 601752 Human
- SwissProt: P49961 Human
- Unigene: 576612 Human
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Form
There are 3 isoforms produced by alternative splicing. -
Alternative names
- ATPDase antibody
- CD 39 antibody
- CD39 antibody
see all
Datasheets and documents
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Datasheet download
References (3)
ab30424 has been referenced in 3 publications.
- Jandus C et al. Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides. Arthritis Rheum 58:2307-17 (2008). Flow Cyt ; Human . PubMed: 18668556
- Valencic E et al. T cells stimulated in vitro have a suppressive function but do not contain only regulatory T cells. Clin Exp Immunol 150:561-6 (2007). Flow Cyt ; Human . PubMed: 17900303
- Aversa GG et al. Detection of a late lymphocyte activation marker by A1, a new monoclonal antibody. Transplant Proc 20:49-52 (1988). PubMed: 2830689