Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionIn the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation. Hydrolyzes ATP and ADP equally well.
Tissue specificityExpressed primarily on activated lymphoid cells. Also expressed in endothelial tissues. The vascular isoform and the placental isoform II are present in both placenta and umbilical vein, whereas placental isoform I is present in placenta only.
Sequence similaritiesBelongs to the GDA1/CD39 NTPase family.
Post-translational modificationsThe N-terminus is blocked. Palmitoylated in the N-terminal part.