Overview

  • Product nameAnti-CD42a antibody [EPR5295]
    See all CD42a primary antibodies
  • Description
    Rabbit monoclonal [EPR5295] to CD42a
  • Tested applicationsWBmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in the extracellular domain of human CD42a

  • Positive control
    • Human platelet lysate
  • General notes

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

  • FormLiquid
  • Storage instructionsStore at -20°C. Stable for 12 months at -20°C
  • Storage bufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • PurityTissue culture supernatant
  • Clonality Monoclonal
  • Clone numberEPR5295
  • IsotypeIgG
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab108304 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 19 kDa.
  • Application notesIs unsuitable for ICC,IHC-P or IP.
  • Target

    • FunctionThe GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
    • Involvement in diseaseDefects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
    • Sequence similaritiesContains 1 LRR (leucine-rich) repeat.
      Contains 1 LRRCT domain.
      Contains 1 LRRNT domain.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD42a antibody
      • Glycoprotein 9 antibody
      • Glycoprotein IX antibody
      • Glycoprotein IX (platelet) antibody
      • Glycoprotein IX precursor antibody
      • GP IX antibody
      • GP-IX antibody
      • GP9 antibody
      • GPIX antibody
      • GPIX_HUMAN antibody
      • Platelet glycoprotein IX antibody
      see all

    Anti-CD42a antibody [EPR5295] images

    • Anti-CD42a antibody [EPR5295] (ab108304) at 1/1000 dilution + Human platelet lysate at 10 µg

      Performed under reducing conditions.

      Predicted band size : 19 kDa

    References for Anti-CD42a antibody [EPR5295] (ab108304)

    ab108304 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab108304.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"