Recombinant
RabMAb

Anti-CD42a antibody [EPR5295] (ab108304)

Overview

  • Product name
    Anti-CD42a antibody [EPR5295]
    See all CD42a primary antibodies
  • Description
    Rabbit monoclonal [EPR5295] to CD42a
  • Tested applications
    Suitable for: WBmore details
    Unsuitable for: ICC,IHC-P or IP
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to residues in the extracellular domain of human CD42a

  • Positive control
    • Human platelet lysate
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

     

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • Storage buffer
    PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
  • Purity
    Tissue culture supernatant
  • Clonality
    Monoclonal
  • Clone number
    EPR5295
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab108304 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 19 kDa.
  • Application notes
    Is unsuitable for ICC,IHC-P or IP.
  • Target

    • Function
      The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
    • Involvement in disease
      Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
    • Sequence similarities
      Contains 1 LRR (leucine-rich) repeat.
      Contains 1 LRRCT domain.
      Contains 1 LRRNT domain.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD42a antibody
      • Glycoprotein 9 antibody
      • Glycoprotein IX antibody
      • Glycoprotein IX (platelet) antibody
      • Glycoprotein IX precursor antibody
      • GP IX antibody
      • GP-IX antibody
      • GP9 antibody
      • GPIX antibody
      • GPIX_HUMAN antibody
      • Platelet glycoprotein IX antibody
      see all

    Images

    • Anti-CD42a antibody [EPR5295] (ab108304) at 1/1000 dilution + Human platelet lysate at 10 µg

      Performed under reducing conditions.

      Predicted band size : 19 kDa

    References

    ab108304 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab108304.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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