Anti-CD42a antibody [GR-P] (CF405M) (ab119483)

Overview

  • Product nameAnti-CD42a antibody [GR-P] (CF405M)
    See all CD42a primary antibodies
  • Description
    Mouse monoclonal [GR-P] to CD42a (CF405M)
  • ConjugationCF405M. Ex: 408nm, Em: 452nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human red blood cells and platelets.

  • Positive control
    • Human platelets in normal peripheral blood.
  • General notes

    CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C.
  • Storage bufferpH: 7.20
    Preservative: 0.09% Sodium azide
    Note: Buffer containing antibody stabilizer solution.
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • ClonalityMonoclonal
  • Clone numberGR-P
  • IsotypeIgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab119483 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 5µl for 106 cells. ab126036-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.

Target

  • FunctionThe GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
  • Involvement in diseaseDefects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
  • Sequence similaritiesContains 1 LRR (leucine-rich) repeat.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD42a antibody
    • Glycoprotein 9 antibody
    • Glycoprotein IX antibody
    • Glycoprotein IX (platelet) antibody
    • Glycoprotein IX precursor antibody
    • GP IX antibody
    • GP-IX antibody
    • GP9 antibody
    • GPIX antibody
    • GPIX_HUMAN antibody
    • Platelet glycoprotein IX antibody
    see all

Anti-CD42a antibody [GR-P] (CF405M) images

  • ab119483, at 5 µl/106 cells, staining CD42a in Human platelets from normal Human peripheral blood cells by Flow Cytometry. Total events were used for the analysis.

References for Anti-CD42a antibody [GR-P] (CF405M) (ab119483)

ab119483 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"