Overview

  • Product name
    Anti-CD42a antibody [GR-P] (Phycoerythrin)
    See all CD42a primary antibodies
  • Description
    Mouse monoclonal [GR-P] to CD42a (Phycoerythrin)
  • Conjugation
    Phycoerythrin. Ex: 488nm, Em: 575nm
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human red blood cells and platelets

  • Positive control
    • Human peripheral blood platelets

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purification notes
    ab30399 was purified by ion exchange chromatography.
  • Clonality
    Monoclonal
  • Clone number
    GR-P
  • Myeloma
    NS1
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab30399 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notes
    Flow Cyt: Use neat, or 10µl for 106 cells or 100µl whole blood.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis. GP-IX may provide for membrane insertion and orientation of GP-Ib.
    • Involvement in disease
      Defects in GP9 are a cause of Bernard-Soulier syndrome (BSS) [MIM:231200]; also known as giant platelet disease (GPD). BSS patients have unusually large platelets and have a clinical bleeding tendency.
    • Sequence similarities
      Contains 1 LRR (leucine-rich) repeat.
      Contains 1 LRRCT domain.
      Contains 1 LRRNT domain.
    • Cellular localization
      Membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD42a antibody
      • Glycoprotein 9 antibody
      • Glycoprotein IX antibody
      • Glycoprotein IX (platelet) antibody
      • Glycoprotein IX precursor antibody
      • GP IX antibody
      • GP-IX antibody
      • GP9 antibody
      • GPIX antibody
      • GPIX_HUMAN antibody
      • Platelet glycoprotein IX antibody
      see all

    Images

    • Staining of human peripheral blood platelets with ab30399.

    References

    This product has been referenced in:
    • Tehrani S  et al. High-dose aspirin is required to influence plasma fibrin network structure in patients with type 1 diabetes. Diabetes Care 35:404-8 (2012). Flow Cyt ; Human . Read more (PubMed: 22148098) »

    See 1 Publication for this product

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab30399.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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