Overview

  • Product name
    Anti-CD42b antibody [AK2] (Biotin)
    See all CD42b primary antibodies
  • Description
    Mouse monoclonal [AK2] to CD42b (Biotin)
  • Conjugation
    Biotin
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control
    • Human peripheral blood platelets
  • General notes


    Clone AK2 has been reported to block the binding of von Willebrand Factor to platelets.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: 1% BSA, PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Protein G purified
  • Primary antibody notes
    Clone AK2 has been reported to block the binding of von Willebrand Factor to platelets.
  • Clonality
    Monoclonal
  • Clone number
    AK2
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab30400 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

Use neat or 10µl for 100µl of whole blood.





ab18434-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

Target

  • Relevance
    CD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF.
  • Cellular localization
    Cell Membrane
  • Database links
  • Alternative names
    • Antigen CD42b alpha antibody
    • BDPLT1 antibody
    • BDPLT3 antibody
    • BSS antibody
    • CD 42b antibody
    • CD42b alpha antibody
    • CD42B antibody
    • CD42b antigen antibody
    • DBPLT3 antibody
    • GLYCOCALICIN antibody
    • Glycoprotein Ib (platelet) alpha polypeptide antibody
    • Glycoprotein Ibalpha antibody
    • GP Ib alpha antibody
    • GP1B antibody
    • GP1BA antibody
    • GPIb alpha antibody
    • GPIbA antibody
    • MGC34595 antibody
    • Platelet glycoprotein Ib alpha chain antibody
    • Platelet glycoprotein Ib alpha polypeptide antibody
    • Platelet membrane glycoprotein 1b alpha subunit antibody
    • VWDP antibody
    see all

Anti-CD42b antibody [AK2] (Biotin) images

  • Flow cytometric analysis of CD42b expressing cells in human periferal blood platelets using ab30400.

References for Anti-CD42b antibody [AK2] (Biotin) (ab30400)

This product has been referenced in:
  • Kumar RA  et al. Kinetics of GPIbalpha-vWF-A1 tether bond under flow: effect of GPIbalpha mutations on the association and dissociation rates. Biophys J 85:4099-109 (2003). Read more (PubMed: 14645097) »

See 1 Publication for this product

Product Wall

Thank you for contacting us.
Please order the following antibody as isotype control.
ab18434; http://www.abcam.com/Mouse-IgG1-MOPC-21-Biotin-isotype-control-ab18434.html
I hope this information is helpful to you. Please do not hesitate t...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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