Overview

  • Product nameAnti-CD42b antibody [HIP1]
    See all CD42b primary antibodies
  • Description
    Mouse monoclonal [HIP1] to CD42b
  • SpecificityCD42b antigen
  • Tested applicationsSuitable for: Flow Cyt, Functional Studies, IHC-Frmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue/ cell preparation (Human). Peripheral blood mononuclear cells of a patient suffering with CLL.

Properties

  • FormLiquid
  • Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage bufferPreservative: 15mM Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • Purity>95% by SDS-PAGE
  • Purification notesPurified from ascites by protein G-affinity chromatography.
  • ClonalityMonoclonal
  • Clone numberHIP1
  • Myelomaunknown
  • IsotypeIgG1
  • Light chain typeunknown
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab2578 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.
Functional Studies Use at an assay dependent concentration. Inhibits the ristocetin-dependent binding of von Willebrand Factor (vWF) to platelets and ristocetin-induced platelet agglutination.
IHC-Fr Use at an assay dependent concentration.

Target

  • RelevanceCD42b is a platelet activation marker involved in the process of coagulation as an aggregating factor. It interacts with extracellular matrix as well as with adhesion molecules. Its expression and activation seems to be regulated by VEGF and PDGF.
  • Cellular localizationCell Membrane
  • Database links
  • Alternative names
    • Antigen CD42b alpha antibody
    • BDPLT1 antibody
    • BDPLT3 antibody
    • BSS antibody
    • CD 42b antibody
    • CD42b alpha antibody
    • CD42B antibody
    • CD42b antigen antibody
    • DBPLT3 antibody
    • GLYCOCALICIN antibody
    • Glycoprotein Ib (platelet) alpha polypeptide antibody
    • Glycoprotein Ibalpha antibody
    • GP Ib alpha antibody
    • GP1B antibody
    • GP1BA antibody
    • GPIb alpha antibody
    • GPIbA antibody
    • MGC34595 antibody
    • Platelet glycoprotein Ib alpha chain antibody
    • Platelet glycoprotein Ib alpha polypeptide antibody
    • Platelet membrane glycoprotein 1b alpha subunit antibody
    • VWDP antibody
    see all

References for Anti-CD42b antibody [HIP1] (ab2578)

This product has been referenced in:
  • Mitchell J & Sullam PM Streptococcus mitis phage-encoded adhesins mediate attachment to {alpha}2-8-linked sialic acid residues on platelet membrane gangliosides. Infect Immun 77:3485-90 (2009). Read more (PubMed: 19506011) »
  • Kishimoto T. (Eds.) et al. Leuccyte typing VI. Garland Publishing Inc. : (1997). Read more (PubMed: ) »

See all 2 Publications for this product

Product Wall

Thank you for your recent telephone enquiry.  I have obtained the following information: The following CD42b antibodies have been tested and guaranteed in functional studies: ab2578 CD42b antibody [HIP1] Click here (or use the f...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"