Anti-CD42d antibody [CLB-SW16 (formerly 708)] (ab23773)

Overview

  • Product name
    Anti-CD42d antibody [CLB-SW16 (formerly 708)]
    See all CD42d primary antibodies
  • Description
    Mouse monoclonal [CLB-SW16 (formerly 708)] to CD42d
  • Specificity
    ab23773 reacts with human platelets. It does not react with lymphocytes, granulocytes, monocytes and erythrocytes.
  • Tested applications
    Suitable for: Functional Studies, ICC/IF, Flow Cyt, ICCmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Tissue/ cell preparation (Human platelets).

  • General notes


    ab23773 does not inhibit the von Willebrand factor-mediated agglutination of fixed platelets induced by 1.25 mg/ml of ristocetin in the presence of human platelets.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Store In the Dark.
  • Storage buffer
    Preservative: 0.001% Thimerosal (merthiolate)
    Constituents: 10mg/ml BSA, 20mM Tris, 150mM Sodium chloride, pH 8.0
  • Concentration information loading...
  • Purity
    Ascites
  • Purification notes
    Purified by ammonium sulphate precipitation and ion exchange chromatography.
  • Primary antibody notes
    ab23773 does not inhibit the von Willebrand factor-mediated agglutination of fixed platelets induced by 1.25 mg/ml of ristocetin in the presence of human platelets.
  • Clonality
    Monoclonal
  • Clone number
    CLB-SW16 (formerly 708)
  • Isotype
    IgG1
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab23773 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Functional Studies Use at an assay dependent concentration.
ICC/IF Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
ICC Use at an assay dependent concentration.

Target

  • Function
    The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.
  • Tissue specificity
    Platelets and megakaryocytes.
  • Sequence similarities
    Contains 13 LRR (leucine-rich) repeats.
    Contains 1 LRRCT domain.
    Contains 1 LRRNT domain.
  • Post-translational
    modifications
    The N-terminus is blocked.
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD 42d antibody
    • CD42d antibody
    • CD42d antigen antibody
    • Glycoprotein 5 antibody
    • Glycoprotein V antibody
    • Glycoprotein V platelet antibody
    • GlycoproteinV antibody
    • Gp 5 antibody
    • GP V antibody
    • GP5 antibody
    • GPV antibody
    • GPV_HUMAN antibody
    • Platelet glycoprotein V antibody
    • Platelet glycoprotein V precursor antibody
    see all

References for Anti-CD42d antibody [CLB-SW16 (formerly 708)] (ab23773)

ab23773 has not yet been referenced specifically in any publications.

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application
Immunocytochemistry
Sample
Human Cell (platelets)
Specification
platelets
Fixative
Paraformaldehyde
Blocking step
BSA as blocking agent for 30 minute(s) · Concentration: 0.1%
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Submitted Jan 23 2007

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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