Overview

  • Product name
    Anti-CD48 antibody [HM48-1]
    See all CD48 primary antibodies
  • Description
    Armenian Hamster monoclonal [HM48-1] to CD48
  • Tested applications
    Suitable for: Flow Cyt, IP, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Mouse T lymphoma MBL2

  • Positive control
    • BALB/c splenocytes
  • General notes


    HM48-1 is reported to modulate in vitro and in vivo CD48 functions including blocking the CD48/CD2 and CD48/CD244 interactions, inhibiting the proliferative response of mitogen-activated spleen cells, providing a costimulation signal for T cells activated in vitro through their TCR, and prolonging cardiac allograft survival in vivo.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS, 150mM Sodium chloride, pH 7.2
  • Concentration information loading...
  • Purity
    Protein G purified
  • Primary antibody notes
    HM48-1 is reported to modulate in vitro and in vivo CD48 functions including blocking the CD48/CD2 and CD48/CD244 interactions, inhibiting the proliferative response of mitogen-activated spleen cells, providing a costimulation signal for T cells activated in vitro through their TCR, and prolonging cardiac allograft survival in vivo.
  • Clonality
    Monoclonal
  • Clone number
    HM48-1
  • Isotype
    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab95606 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 0.5µg for 105-8 cells. Staining the cell sample in a final volume of 100 µL is recommended.



ab18479-Armenian Hamster monoclonal IgG, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 28 kDa.

Target

  • Function
    Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.
  • Sequence similarities
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.
  • Cellular localization
    Cell membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • Antigen CD48 antibody
    • B cell membrane protein antibody
    • B lymphocyte activation marker BLAST 1 antibody
    • B-cell activation marker antibody
    • B-lymphocyte activation marker BLAST-1 antibody
    • BCM 1 surface antigen antibody
    • BCM1 antibody
    • BCM1 surface antigen antibody
    • BLAST 1 antibody
    • BLAST antibody
    • BLAST1 antibody
    • CD 48 antibody
    • CD48 antibody
    • CD48 antigen (B cell membrane protein) antibody
    • CD48 antigen antibody
    • CD48 molecule antibody
    • CD48 protein antibody
    • CD48_HUMAN antibody
    • hCD48 antibody
    • Leucocyte antigen MEM 102 antibody
    • Leukocyte antigen MEM-102 antibody
    • mCD48 antibody
    • MEM 102 antibody
    • MEM-102 antibody
    • MEM102 antibody
    • Signaling lymphocytic activation molecule 2 antibody
    • SLAM family member 2 antibody
    • SLAMF 2 antibody
    • SLAMF2 antibody
    • TCT.1 antibody
    see all

Images

  • Staining of BALB/c splenocytes with 0.25 µg of Armenian Hamster IgG Isotype Control Purified (open histogram) or 0.25 µg of ab95606 (filled histogram) followed by Anti-Armenian Hamster IgG FITC. Total viable cells were used for analysis.

References

This product has been referenced in:
  • Möller J  et al. Macrophages lift off surface-bound bacteria using a filopodium-lamellipodium hook-and-shovel mechanism. Sci Rep 3:2884 (2013). Mouse . Read more (PubMed: 24097079) »

See 1 Publication for this product

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There are currently no Customer reviews or Questions for ab95606.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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