Anti-CD49b antibody [TEA1/41] (CF405M) (ab115797)


  • Product nameAnti-CD49b antibody [TEA1/41] (CF405M)
    See all CD49b primary antibodies
  • Description
    Mouse monoclonal [TEA1/41] to CD49b (CF405M)
  • ConjugationCF405M. Ex: 408nm, Em: 452nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control
    • Human platelets (peripheral blood).
  • General notes

    CF405M (Abs/Em Max: 408/450 nm) US patent application no. 12/607,915. CF405M (Abs/Em Max: 408/450nm). Direct replacement for Pacific Blue dye®, BD Horizon™ V450.



Our Abpromise guarantee covers the use of ab115797 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 5µl for 106 cells.

ab126026 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.


  • RelevanceHuman CD49b is an integrin alpha 2 subunit that forms a heterodimer with beta 1 integrin and functions as an adhesion molecule. CD49b is a 160 kDa glycoprotein that noncovalently associates with the 130 kDa integrin beta 1 subunit (CD29) to form glycoprotein Ia/IIa (when expressed on platelets), and very late (activation) antigen 2 ('VLA2') when found on T cells. CD49b is expressed by platelets, approximately 50% of monocytes, long term cultivated T cells and most adherent cell lines. Integrin alpha 2/beta 1 is a receptor for laminin, collagen, collagen C propeptides, fibronectin and E cadherin. It recognizes the proline hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
  • Cellular localizationCell Membrane; Single pass type I membrane protein.
  • Database links
  • Alternative names
    • BR antibody
    • CD49 antigen like family member B antibody
    • CD49B antibody
    • Collagen Receptor antibody
    • GPla antibody
    • HPA 5 antibody
    • Human platelet alloantigen system 5 antibody
    • Integrin alpha 2 antibody
    • Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA 2 receptor) antibody
    • Itga2 antibody
    • platelet antigen Br antibody
    • platelet glycoprotein GPIa antibody
    • platelet glycoprotein Ia antibody
    • Platelet membrane glycoprotein 1a antibody
    • platelet membrane glycoprotein Ia antibody
    • very late activation protein 2 receptor alpha 2 subunit antibody
    • VLA 2 antibody
    • VLA 2 subunit alpha antibody
    • VLA2 alpha chain antibody
    • VLA2 antibody
    • VLA2 receptor, alpha 2 subunit antibody
    • VLA2 subunit alpha antibody
    • VLAA2 antibody
    see all

Anti-CD49b antibody [TEA1/41] (CF405M) images

  • ab115797 at 5µl/106 cells staining CD49b in Human platelets by Flow Cytometry (shown in red).
    Isotype control (blue).

References for Anti-CD49b antibody [TEA1/41] (CF405M) (ab115797)

ab115797 has not yet been referenced specifically in any publications.

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