Overview

  • Product nameAnti-CD5 antibody [EP2952]
    See all CD5 primary antibodies
  • Description
    Rabbit monoclonal [EP2952] to CD5
  • Tested applicationsSuitable for: WB, IP, IHC-P, ICCmore details
    Unsuitable for: Flow Cyt
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide from human CD5.

  • Positive control
    • Human tonsil tissue.
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

     

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

Properties

Applications

Our Abpromise guarantee covers the use of ab75877 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/50000. Predicted molecular weight: 55 kDa.
IP 1/50.
IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ICC 1/100 - 1/250.
  • Application notesIs unsuitable for Flow Cyt.
  • Target

    • FunctionMay act as a receptor in regulating T-cell proliferation. CD5 interacts with CD72/LYB-2.
    • Sequence similaritiesContains 3 SRCR domains.
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD 5 antibody
      • CD5 antibody
      • CD5 antigen (p56 62) antibody
      • CD5 antigen antibody
      • CD5 molecule antibody
      • CD5_HUMAN antibody
      • LEU1 antibody
      • LyA antibody
      • Lymphocyte antigen T1/Leu-1 antibody
      • OTTHUMP00000236973 antibody
      • T-cell surface glycoprotein CD5 antibody
      • T1 antibody
      see all

    Anti-CD5 antibody [EP2952] images

    • ab75877 showing positive staining in Normal colon lymphocytes tissue.

    • ab75877 showing negative staining in Normal brain tissue.

    • ab75877 showing negative staining in Normal kidney tissue.

    • ab75877 showing negative staining in Skeletal muscle tissue.

    • ab75877 showing positive staining in Normal spleen tissue.

    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References for Anti-CD5 antibody [EP2952] (ab75877)

    This product has been referenced in:
    • Xiao LI  et al. Multiple myeloma-associated skin light chain amyloidosis: A case of misdiagnosis. Oncol Lett 11:3617-3620 (2016). IHC ; Human . Read more (PubMed: 27284363) »
    • Lu TX  et al. Epstein-Barr virus positive diffuse large B-cell lymphoma predict poor outcome, regardless of the age. Sci Rep 5:12168 (2015). IHC ; Human . Read more (PubMed: 26202875) »

    See all 2 Publications for this product

    Product Wall

    According to the datasheet, this antibody is indeed a non-purified cell culture supernatantproduct. That means, along with whole serum and Ascitesproducts, the antibody concentration cannot be determined as there are too many other proteins in this sol...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"