Anti-CD51 + CD61 antibody [23C6] (FITC) (ab93513)

Overview

  • Product nameAnti-CD51 + CD61 antibody [23C6] (FITC)
    See all CD51 + CD61 primary antibodies
  • Description
    Mouse monoclonal [23C6] to CD51 + CD61 (FITC)
  • ConjugationFITC. Ex: 493nm, Em: 528nm
  • Tested applicationsSuitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Cell preparation: cell suspension containing osteoclasts from osteoclastomas.

  • Positive control
    • M21 cells

Properties

Applications

Our Abpromise guarantee covers the use of ab93513 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
  • Application notesFlow Cyt: Use 5µl/test in 100µl volume.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • RelevanceIntegrins are integral cell-surface proteins composed of an alpha chain and a beta chain. They are known to participate in cell adhesion as well as cell-surface mediated signalling. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. CD51 encodes integrin alpha chain V. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. The CD61 protein product is the integrin beta chain beta 3. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrin alpha V/beta 3 is a receptor for cytotactin, fibronectin, laminin, matrix metalloproteinase 2, osteopontin, osteomodulin, prothrombin, thrombospondin, vitronectin and von Willebrand factor. Integrin alpha V/beta 3 recognizes the sequence R-G-D in a wide array of ligands. The alpha V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase 2, osteopontin, osteomodulin, prothrombin, thrombospondin and von Willebrand factor. They recognize the sequence R-G-D in a wide array of ligands.
    • Cellular localizationCell Membrane; single-pass type I membrane protein.
    • Database links
    • Alternative names
      • Antigen identified by monoclonal antibody L230 antibody
      • CD51 antibody
      • CD51 antigen antibody
      • CD61 antibody
      • CD61 antigen antibody
      • DKFZp686A08142 antibody
      • GP3A antibody
      • GPIIIa antibody
      • Integrin alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody
      • Integrin alpha v antibody
      • Integrin beta 3 (platelet glycoprotein IIIa, antigen CD61) antibody
      • Integrin beta 3 antibody
      • Integrin beta chain beta 3 antibody
      • ITGAV antibody
      • ITGB3 antibody
      • MSK8 antibody
      • Platelet glycoprotein IIIa antibody
      • Platelet membrane glycoprotein IIIa antibody
      • Vitronectin receptor subunit alpha antibody
      • VNRA antibody
      see all

    Anti-CD51 + CD61 antibody [23C6] (FITC) images

    • ab93513 at 5µl/test staining CD51 + CD61 in M21 cells (blue histogram) or FITC mouse IgG1, k Isotype control (green histogram). Total viable cells were used for analysis.

    References for Anti-CD51 + CD61 antibody [23C6] (FITC) (ab93513)

    ab93513 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"