Overview

  • Product name
    Anti-CD57 antibody [TB01]
    See all CD57 primary antibodies
  • Description
    Mouse monoclonal [TB01] to CD57
  • Specificity
    This antibody is specific for CD57.
  • Tested applications
    Suitable for: Flow Cyt, IHC-Fr, IHC-Pmore details
    Unsuitable for: IP or WB
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Human neuroblastoma cells

  • Positive control
    • Human tonsil tissue.

Properties

  • Form
    Liquid
  • Storage instructions
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer
    Preservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • Purity
    Ion Exchange Chromatography
  • Clonality
    Monoclonal
  • Clone number
    TB01
  • Myeloma
    P3x63-Ag8.653
  • Isotype
    IgM
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab33273 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt
IHC-Fr
IHC-P
  • Application notes
    Flow Cyt: 1/50 - 1/100.
    Use 10µl of the suggested working dilution to label 106 cells in 100µl.

    IHC-Fr: 1/10 - 1/100.
    IHC-P: 1/10 - 1/50.

    This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections but sodium citrate buffer may enhance staining.

    Is unsuitable for IP or WB.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function
      Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
    • Tissue specificity
      Mainly expressed in the brain.
    • Pathway
      Protein modification; protein glycosylation.
    • Sequence similarities
      Belongs to the glycosyltransferase 43 family.
    • Cellular localization
      Golgi apparatus membrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • 3-glucuronyltransferase 1 antibody
      • 3-glucuronyltransferase antibody
      • B3GA1_HUMAN antibody
      • B3gat1 antibody
      • Beta 1 3 glucuronyltransferase 1 antibody
      • Beta-1 antibody
      • Beta-1,3-glucuronyltransferase 1 antibody
      • CD 57 antibody
      • CD57 antibody
      • CD57 antigen antibody
      • Galactosylgalactosylxylosylprotein 3 beta glucuronosyltransferase 1 antibody
      • Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1 antibody
      • GlcAT P antibody
      • GlcAT-P antibody
      • GLCATP antibody
      • GlcUAT P antibody
      • GlcUAT-P antibody
      • GlcUATP antibody
      • Glucuronosyltransferase P antibody
      • HNK 1 antibody
      • HNK1 antibody
      • LEU 7 antibody
      • LEU7 antibody
      • LEU7 antigen antibody
      • NK 1 antibody
      • NK1 antibody
      • UDP GlcUA glycoprotein beta 1 3 glucuronyltransferase antibody
      • UDP-GlcUA:glycoprotein beta-1 antibody
      see all

    References for Anti-CD57 antibody [TB01] (ab33273)

    This product has been referenced in:
    • Eriksson M  et al. Unique phenotype of human uterine NK cells and their regulation by endogenous TGF-beta. J Leukoc Biol 76:667-75 (2004). Read more (PubMed: 15178706) »

    See 1 Publication for this product

    Product Wall

    There are currently no Abreviews or Questions for ab33273.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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