• Product nameAnti-CD6 antibody [EPR4056]
    See all CD6 primary antibodies
  • Description
    Rabbit monoclonal [EPR4056] to CD6
  • Tested applicationsSuitable for: WB, IP, IHC-Pmore details
    Unsuitable for: Flow Cyt or ICC
  • Species reactivity
    Reacts with: Human
  • Immunogen

    A synthetic peptide corresponding to residues in Human CD6.

  • Positive control
    • WB: Jurkat, HuT-78, PBMC and Human tonsil lysates IHC-P: Human tonsil and Human lymphocytes infiltrating colon tissues
  • General notes

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.


Associated products


Our Abpromise guarantee covers the use of ab109218 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 90-130 kDa (predicted molecular weight: 72 kDa).
IP 1/10 - 1/100.
IHC-P 1/250 - 1/500. Antigen retrieval is recommended.
  • Application notesIs unsuitable for Flow Cyt or ICC.
  • Target

    • FunctionInvolved in cell adhesion. Binds to CD166.
    • Tissue specificityExpressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
    • Sequence similaritiesContains 3 SRCR domains.
    • Post-translational
      After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
      Contains intrachain disulfide bond(s).
    • Cellular localizationMembrane.
    • Information by UniProt
    • Database links
    • Alternative names
      • CD_antigen=CD6 antibody
      • CD6 antibody
      • CD6 antigen Tp120 antibody
      • CD6 molecule antibody
      • CD6_HUMAN antibody
      • FLJ44171 antibody
      • OX52 antibody
      • T cell differentiation antigen CD6 antibody
      • T-cell differentiation antigen CD6 antibody
      • T12 antibody
      • TP120 antibody
      see all

    Anti-CD6 antibody [EPR4056] images

    • All lanes : Anti-CD6 antibody [EPR4056] (ab109218) at 1/1000 dilution

      Lane 1 : Jurkat lysates
      Lane 2 : HuT-78 lysates
      Lane 3 : PBMC lysates
      Lane 4 : Human tonsil lysates

      Lysates/proteins at 10 µg per lane.

      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 72 kDa
      Observed band size : 90-130 kDa (why is the actual band size different from the predicted?)
    • ab109218, at a 1/100 dilution, staining CD6 in paraffin embedded Human tonsil tissue by Immunohistochemistry.
    • ab109218, at a 1/100 dilution, staining CD6 in paraffin embedded Human lymphocytes infiltrating colon tissue by Immunohistochemistry.
    • ab109218 showing negative staining in Normal kidney tissue.

    • ab109218 showing negative staining in Normal uterus tissue.

    • ab109218 showing negative staining in Normal brain tissue.

    References for Anti-CD6 antibody [EPR4056] (ab109218)

    ab109218 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab109218.
    Please use the links above to contact us or submit feedback about this product.