Anti-CD6 antibody [MAE-1C10] (Allophycocyanin) (ab90897)

Overview

  • Product name
    Anti-CD6 antibody [MAE-1C10] (Allophycocyanin)
    See all CD6 primary antibodies
  • Description
    Mouse monoclonal [MAE-1C10] to CD6 (Allophycocyanin)
  • Conjugation
    Allophycocyanin. Ex: 645nm, Em: 660nm
  • Tested applications
    Suitable for: Flow Cytmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length purified native protein.

  • Positive control
    • Anticoagulated (EDTA) normal peripheral blood. The antigen is found on >80% normal mature T cells and a sub-population of B cells in peripheral blood. CD6 also exhibits weak expression on cortical thymocytes and the majority of chronic B lymphocytic leukaemias.

Properties

Applications

Our Abpromise guarantee covers the use of ab90897 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use 20µl for 106 cells.

Target

  • Function
    Involved in cell adhesion. Binds to CD166.
  • Tissue specificity
    Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
  • Sequence similarities
    Contains 3 SRCR domains.
  • Post-translational
    modifications
    After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
    Contains intrachain disulfide bond(s).
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD_antigen=CD6 antibody
    • CD6 antibody
    • CD6 antigen Tp120 antibody
    • CD6 molecule antibody
    • CD6_HUMAN antibody
    • FLJ44171 antibody
    • OX52 antibody
    • T cell differentiation antigen CD6 antibody
    • T-cell differentiation antigen CD6 antibody
    • T12 antibody
    • TP120 antibody
    see all

Images

  • Flow cytometry analysis of CD6 in normal peripheral blood from a Human donor using ab90897 at 20 µl/106 cells. Encircled are CD6+ T cells and a subset of B cells.

References

ab90897 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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