Overview

  • Product name
    Anti-CD6 antibody [MEM-98]
    See all CD6 primary antibodies
  • Description
    Mouse monoclonal [MEM-98] to CD6
  • Specificity
    CD6 antigen (human)
  • Tested applications
    Suitable for: Flow Cyt, IP, WB, IHC-Pmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    CD6 antigen purified by immunoaffinity chromatography from HBP ALL cells followed by preparative SDS-PAGE of non-boiled non-reduced sample (excised piece of gel corresponding to the 100 kDa zone).

  • Positive control
    • Spleen.
  • General notes

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

Properties

Applications

Our Abpromise guarantee covers the use of ab9181 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use a concentration of 2 µg/ml. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
IP Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Use under non reducing condition.
IHC-P Use a concentration of 10 µg/ml.

Target

  • Function
    Involved in cell adhesion. Binds to CD166.
  • Tissue specificity
    Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
  • Sequence similarities
    Contains 3 SRCR domains.
  • Post-translational
    modifications
    After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
    Contains intrachain disulfide bond(s).
  • Cellular localization
    Membrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD_antigen=CD6 antibody
    • CD6 antibody
    • CD6 antigen Tp120 antibody
    • CD6 molecule antibody
    • CD6_HUMAN antibody
    • FLJ44171 antibody
    • OX52 antibody
    • T cell differentiation antigen CD6 antibody
    • T-cell differentiation antigen CD6 antibody
    • T12 antibody
    • TP120 antibody
    see all

References

This product has been referenced in:
  • Bazil V  et al. Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102. Folia Biol (Praha) 35:289-97 (1989). Read more (PubMed: 2534480) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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