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Mouse monoclonal [MRC OX-52] to CD6
Recognises a cell surface structure with two chains of 95kD and 120kD expressed by rat T lymphocytes and thymocytes. It does not label B lymphocytes, granulocytes or macrophages although it gives faint labelling of dendritic cells.
Tissue/ cell preparation of thoracic duct lymphocytes (Rat).
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use 10µl for 10
6 cells. ab170191-Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
Use at an assay dependent concentration.
Involved in cell adhesion. Binds to CD166.
Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain.
Contains 3 SRCR domains.
After T-cell activation, becomes hyperphosphorylated on Ser and Thr residues and phosphorylated on Tyr residues.
Contains intrachain disulfide bond(s).
Information by UniProt
CD6 antigen Tp120 antibody
References for Anti-CD6 antibody [MRC OX-52] (ab22381)
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"