Anti-CD62E antibody [UZ6] (ab2497)
Key features and details
- Rat monoclonal [UZ6] to CD62E
- Suitable for: ICC/IF
- Reacts with: Mouse
- Isotype: IgG2b
Overview
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Product name
Anti-CD62E antibody [UZ6]
See all CD62E primary antibodies -
Description
Rat monoclonal [UZ6] to CD62E -
Host species
Rat -
Tested applications
Suitable for: ICC/IFmore details -
Species reactivity
Reacts with: Mouse -
Positive control
- ICC/IF: CHO-cells transfected with E-Selectin.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
UZ6 -
Myeloma
Sp2/0 -
Isotype
IgG2b -
Research areas
Associated products
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Compatible Secondaries
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Conjugation kits
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab2497 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ICC/IF |
Use at an assay dependent concentration.
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Notes |
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ICC/IF
Use at an assay dependent concentration. |
Target
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Function
Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis. -
Sequence similarities
Belongs to the selectin/LECAM family.
Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.
Contains 6 Sushi (CCP/SCR) domains. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 20339 Mouse
- SwissProt: Q00690 Mouse
- Unigene: 5245 Mouse
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Alternative names
- CD26E antibody
- CD62 antigen-like family member E antibody
- CD62E antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (6)
ab2497 has been referenced in 6 publications.
- Schimmel K et al. Combined high-throughput library screening and next generation RNA sequencing uncover microRNAs controlling human cardiac fibroblast biology. J Mol Cell Cardiol 150:91-100 (2021). PubMed: 33127387
- Sakamoto T et al. Pharmacological inhibition of Mint3 attenuates tumour growth, metastasis, and endotoxic shock. Commun Biol 4:1165 (2021). PubMed: 34621018
- Cao H et al. The protective effect of vitexinin septic encephalopathy by reducing leukocyte-endothelial adhesion and inflammatory response. Ann Palliat Med 9:2079-2089 (2020). PubMed: 32692224
- Meng ZD et al. Effects of RNA interference-mediated E-selectin gene silencing on cell adhesion molecule expression and cell-cell adhesion in vascular endothelial cells in mice with immunologic contact urticaria. J Cell Biochem 120:115-125 (2019). PubMed: 30206961
- Sapieha P et al. 5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of ?-3 polyunsaturated fatty acids. Sci Transl Med 3:69ra12 (2011). PubMed: 21307302
- Hammel M et al. Species-specific and conserved epitopes on mouse and human E-selectin important for leukocyte adhesion. Exp Cell Res 269:266-74 (2001). PubMed: 11570819