Overview

  • Product nameAnti-CD62E antibody [UZ6]
    See all CD62E primary antibodies
  • Description
    Rat monoclonal [UZ6] to CD62E
  • Tested applicationsSuitable for: ICC/IF, ELISA, Flow Cyt, IHC-Fr, IP, WBmore details
  • Species reactivity
    Reacts with: Mouse
  • Positive control
    • Tonsil

Properties

Applications

Our Abpromise guarantee covers the use of ab2497 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
ELISA Use at an assay dependent concentration.
Flow Cyt Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.
IP Use at an assay dependent concentration.
WB 1/1000. Predicted molecular weight: 67 kDa.

Target

  • FunctionCell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
  • Sequence similaritiesBelongs to the selectin/LECAM family.
    Contains 1 C-type lectin domain.
    Contains 1 EGF-like domain.
    Contains 6 Sushi (CCP/SCR) domains.
  • Cellular localizationMembrane.
  • Information by UniProt
  • Database links
  • Alternative names
    • CD26E antibody
    • CD62 antigen-like family member E antibody
    • CD62E antibody
    • E selectin antibody
    • E-selectin antibody
    • ELAM antibody
    • ELAM-1 antibody
    • ELAM1 antibody
    • Endothelial adhesion molecule 1 antibody
    • Endothelial leukocyte adhesion molecule 1 antibody
    • ESEL antibody
    • LECAM2 antibody
    • Leukocyte-endothelial cell adhesion molecule 2 antibody
    • LYAM2_HUMAN antibody
    • Sele antibody
    • Selectin E antibody
    see all

References for Anti-CD62E antibody [UZ6] (ab2497)

This product has been referenced in:
  • Sapieha P  et al. 5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of ?-3 polyunsaturated fatty acids. Sci Transl Med 3:69ra12 (2011). Read more (PubMed: 21307302) »
  • Hammel M  et al. Species-specific and conserved epitopes on mouse and human E-selectin important for leukocyte adhesion. Exp Cell Res 269:266-74 (2001). Read more (PubMed: 11570819) »

See all 2 Publications for this product

Product Wall

Thanks you for your email.
In my previous email there is a correction about the expiry date. The expiry date should be read as 25-08-2012.
I have asked lab to release the immunogen information of these antibodies; I will be able to send the a...

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Thank you very much for your email!

I hope you are well as well! Here we are fine - we have one of our first days of spring :-)

In regards to your questions:

The CD62E antibodies ab22631 et ab2497 are two different clones....

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunohistochemistry (Frozen sections)
Sample Mouse Tissue sections (Brain)
Specification Brain
Fixative Paraformaldehyde
Permeabilization No
Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: 20°C
Username

Dr. Thomas Weissensteiner

Verified customer

Submitted Oct 22 2009

1) Crossreactivities: this antibody reacts with mouse E-selectin but not with human E-selectin. Other species not tested. 2)Blocking function: Ab2497 (20 microgram/ml) inhibited up to 70% of mouse PMN and up to 95% of human peripheral blood mononuclea...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"